Cyclophilin 40 Antibody PA3-022 from Thermo Fisher Scientific

Product Specs
ItemCyclophilin 40 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA3-022
ReactivityHuman, Mouse, Rat
TargetCyclophilin 40
HostRabbit
FormatPBS with 1mg/mL BSA and 0.05% sodium azide
Quantity100 µL
ApplicationsFlow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
ClonalityPolyclonal
NCBI Full Gene Namepeptidylprolyl isomerase D, peptidylprolyl isomerase D (cyclophilin D)
ImmunogenSynthetic peptide corresponding to residues C A(356) Q K D K E K A V Y A K M F A(370) of human Cyp-40
IsotypeIgG
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
Concentration1 mg/mL
Antibody TypePrimary
PurityAffinity chromatography
Storage-20°C, Avoid Freeze/Thaw Cycles
Conjugate/TagUnconjugated
NCBI Gene AliasesCypD, CYPD, Cyp-40, 4930564J03Rik, Ppidl, CYP-40

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(1) Mitofilin Preservation Mitigates Cardiac Injury in Donation-After-Circulatory-Death HeartsCellsMay 18, 2026Qun Chen, Zachary Kiernan, Gina Labate, Oluwatoyin Akande, Edward J. Lesnefsky, Mohammed Quader4 °C with primary antibodies (Table 1) against mitofilin and cyclophilin D (1:1000; Thermo Fisher, PA3-022). After four 5 min TBST washes, membranes were incubated for 1 h with HRP-conjugated secondary antibodies

(2) Hydrogen sulfide inhibits Ca²⁺-induced mitochondrial permeability transition pore opening in type-1 diabetesAmerican journal of physiology. Endocrinology and metabolismAugust 1, 2019Papu John AS, Kundu S, Pushpakumar S, Amin M, Tyagi SC, Sen U.were purchased as follows: Anti-Cav1.2 (MAB-13170) from Millipore (Burlington, MA); Cyclophilin D (PA3-022), NMDA-R1 (PA3-102), and TIM-1 (KIM-1) PA5-20244 from Thermo Fisher Scientific (Waltham, MA); ␤-actin

(3) Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampusRedox biologySeptember 1, 2018Jara C, Aránguiz A, Cerpa W, Tapia-Rojas C, Quintanilla RA.Santa Cruz Biotechnology, Inc., 1:1000), rabbit anti-Opa1 (PA1–16991, Thermo Scientific, 1:1000), rabbit anti-Cyclophilin D (PA3–022, Thermo Scientific, 1:1000), rabbit anti-Fis1 (sc-98900, Santa Cruz Biotechnology, Inc., 1:500), rabbit

(4) A mitochondrial division inhibitor, Mdivi-1, inhibits mitochondrial fragmentation and attenuates kainic acid-induced hippocampal cell deathBMC neuroscienceJune 10, 2016Kim H, Lee JY, Park KJ, Kim WH, Roh GS.Hsp72 from Enzo ADI-SPA-812, Opa1 from BD 612606, Mfn2 from Abcam 56889, CypD from Thermo Scientific PA3-022, voltage-dependent anion channel 1 (VDAC1) from Abcam 15895, and β-actin from Sigma-Aldrich A5441) and

(5) FKBP51 controls cellular adipogenesis through p38 kinase-mediated phosphorylation of GRα and PPARγMolecular endocrinology (Baltimore, Md.)August 1, 2014Stechschulte LA, Hinds TD Jr, Khuder SS, Shou W, Najjar SM, Sanchez ER.

(6) Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretionVirology journalJune 28, 2011Anderson LJ, Lin K, Compton T, Wiedmann B.were obtained from Abcam. Rabbit polyclonal antibody to cyclophilin 40 was from Affinity Bioreagents (PA3-022). Mouse anti-PDI antibody was purchased from Assay Designs (SPA-890). Mouse monoclonal antibody to HCV

(7) Identification of cyclophilin-40-interacting proteins reveals potential cellular function of cyclophilin-40Analytical biochemistryMarch 15, 2011Park MS, Chu F, Xie J, Wang Y, Bhattacharya P, Chan WK.β-mercaptoethanol). Samples were analyzed by chemiluminescent Western using the rabbit anti-CyP40 IgG (PA3-022, Thermo Fisher Scientific, Rockford, IL). Using bacterially expressed V5 fusions: 16.5 μl of TALON purified,

(8) Differential impact of tetratricopeptide repeat proteins on the steroid hormone receptorsPloS oneJuly 22, 2010Schülke JP, Wochnik GM, Lang-Rollin I, Gassen NC, Knapp RT, Berning B, Yassouridis A, Rein T.

(9) Susceptibility to diet-induced hepatic steatosis and glucocorticoid resistance in FK506-binding protein 52-deficient miceEndocrinologyJuly 1, 2010Warrier M, Hinds TD Jr, Ledford KJ, Cash HA, Patel PR, Bowman TA, Stechschulte LA, Yong W, Shou W, Najjar SM, et al.

(10) FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin AOncogeneMarch 18, 2010Periyasamy S, Hinds T Jr, Shemshedini L, Shou W, Sanchez ER.the AR, whereas various antibodies were used to probe for FKBP51 (SC11514), actin (SC8432), Cyp40 (PA3–022; Affinity BioReagents). After being probed, blots were incubated with appropriate HRP-conjugated counter

(11) The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear eventsMolecular and cellular biologyMarch 1, 2010Galigniana MD, Erlejman AG, Monte M, Gomez-Sanchez C, Piwien-Pilipuk G.

(12) Targeted ablation reveals a novel role of FKBP52 in gene-specific regulation of glucocorticoid receptor transcriptional activityThe Journal of steroid biochemistry and molecular biologyJanuary 1, 2009Wolf IM, Periyasamy S, Hinds T Jr, Yong W, Shou W, Sanchez ER.a gift from Michael Chinkers (University of South Alabama, College of Medicine, Mobile, AL). Cyp40 (PA3-022) and FKBP52 (UPJ52) antibodies were from Affinity Bioreagents (Golden, CO). Antibodies to FKBP51 (sc-11518),

(13) Control of glucocorticoid and progesterone receptor subcellular localization by the ligand-binding domain is mediated by distinct interactions with tetratricopeptide repeat proteinsBiochemistrySeptember 30, 2008Banerjee A, Periyasamy S, Wolf IM, Hinds TD Jr, Yong W, Shou W, Sanchez ER.IgG (sc-9996) were obtained from Santa Cruz Biotechnologies (Santa Cruz, CA). Antibody against Cyp40 (PA3-022) was purchased from Affinity Bioreagents (Golden, CO). Goat anti-rabbit IgG-HRP conjugate (401315) and

(14) Cyclophilin-40 has a cellular role in the aryl hydrocarbon receptor signalingFEBS lettersSeptember 22, 2008Luu TC, Bhattacharya P, Chan WK.Cell culture reagents were purchased from Sigma and Invitrogen. Antibodies against Arnt (H-172), CyP40 (PA3-022) and GAPDH (6C5) were purchased from Santa Cruz Biotechnology, Affinity Bioreagents and Ambion, respectively.

(15) The immunophilin ligands cyclosporin A and FK506 suppress prostate cancer cell growth by androgen receptor-dependent and -independent mechanismsEndocrinologyOctober 1, 2007Periyasamy S, Warrier M, Tillekeratne MP, Shou W, Sanchez ER.

(16) Essential role for Co-chaperone Fkbp52 but not Fkbp51 in androgen receptor-mediated signaling and physiologyThe Journal of biological chemistryFebruary 16, 2007Yong W, Yang Z, Periyasamy S, Chen H, Yucel S, Li W, Lin LY, Wolf IM, Cohn MJ, Baskin LS, et al.

(17) Physiological role for the cochaperone FKBP52 in androgen receptor signalingMolecular endocrinology (Baltimore, Md.)June 1, 2005Cheung-Flynn J, Prapapanich V, Cox MB, Riggs DL, Suarez-Quian C, Smith DF.

(18) Differential control of glucocorticoid receptor hormone-binding function by tetratricopeptide repeat (TPR) proteins and the immunosuppressive ligand FK506BiochemistryFebruary 15, 2005Davies TH, Ning YM, Sánchez ER.Transduction Laboratories, Inc.), FKBP52 [UPJ56 (23)], FKBP51 (PA0021; Affinity Bioreagents), Cyp40 (PA3-022; Affinity Bioreagents), PP5 [a gift from Dr. Michael Chinkers (18)], and dynein intermediate chain (MAB

(19) Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondriaCirculation researchMay 2, 2003Baines CP, Song CX, Zheng YT, Wang GW, Zhang J, Wang OL, Guo Y, Bolli R, Cardwell EM, Ping P.

(20) p50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase moleculesBiochemistryJune 27, 2000Hartson SD, Irwin AD, Shao J, Scroggins BT, Volk L, Huang W, Matts RL.

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Cyclophilin 40 Antibody

Cyclophilin 40 Antibody from Thermo Fisher Scientific

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Cyclophilin 40 Antibody from Thermo Fisher Scientific

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