Cannabinoid Receptor 1 Antibody PA1-745 from Thermo Fisher Scientific

Product Specs
ItemCannabinoid Receptor 1 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA1-745
NCBI Gene AliasesCB1K5, CNR, CB1R, CB-R, CB1, CB1A, CB1B, CANN6, SKR6R
Quantity100 µL
ApplicationsFlow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
ReactivityAmphibian, Chicken, Fish, Human, Mouse, Non-human primate, Rat
Conjugate/TagUnconjugated
TargetCannabinoid Receptor 1
ClonalityPolyclonal
HostRabbit
FormatPBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
NCBI Full Gene Namecannabinoid receptor 1 (brain), cannabinoid receptor 1
Concentration1.0 mg/mL
ImmunogenA fusion protein containing the first 77 amino acid residues from rat CB1
IsotypeIgG
PurityAffinity chromatography
Antibody TypePrimary
Storage-20° C, Avoid Freeze/Thaw Cycles
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles

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Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Neuroprotective Role of Cannabinoid CB1 and GPR55 Receptors in a Cell Model of Multiple SclerosisMol NeurobiolMarch 3, 2026Eva Martínez-Pinilla, José Manuel Calatayud-Morán, Carlota Menéndez-Pérez, Sandra Villar-Conde, Rafael Rivas-Santisteban, Rafael Peláez, Ana Navarro, Rafael Francocells were incubated overnight at 4 °C in a humidified chamber with a rabbit anti-CB1R antibody (1:500; PA1-745, Thermo Scientific, Rockford, USA). After three PBS washes, cells were incubated for 30 min at room

(2) Fit-for-purpose based testing and validation of antibodies to amino- and carboxy-terminal domains of cannabinoid receptor 1Histochemistry and cell biologyNovember 1, 2021Echeazarra L, García Del Caño G, Barrondo S, González-Burguera I, Saumell-Esnaola M, Aretxabala X, López de Jesús M, Borrega-Román L, Mato S, Ledent C, et al.(Grimsey et al. 2008), authors reported that two commercial antibodies produced against residues 1–77 (PA1-745, Affinity BioReagents) and 1–99 (C1108, Sigma-Aldrich) of the rat and human CB1 receptors, respectively,

(3) Identification of BiP as a CB(1) Receptor-Interacting Protein That Fine-Tunes Cannabinoid Signaling in the Mouse BrainThe Journal of neuroscience : the official journal of the Society for NeuroscienceSeptember 22, 2021Costas-Insua C, Moreno E, Maroto IB, Ruiz-Calvo A, Bajo-Grañeras R, Martín-Gutiérrez D, Diez-Alarcia R, Vilaró MT, Cortés R, García-Font N, et al.Santa Cruz Biotechnology, #sc-376768) and rabbit anti-CB1R antibody (1:100, Thermo Fisher Scientific, #PA1-745)] was used. Samples were analyzed in a Leica SP2 confocal microscope (Leica Microsystems) equipped with

(4) Methamphetamine Blocks Adenosine A(2A) Receptor Activation via Sigma 1 and Cannabinoid CB(1) ReceptorsInternational journal of molecular sciencesMarch 9, 2021Casanovas M, Reyes-Resina I, Lillo A, Lillo J, López-Arnau R, Camarasa J, Escubedo E, Navarro G, Franco R.Ref. 32261) and rabbit polyclonal anti-CB1 R (1/100; ThermoFisher Scientific, Waltham, MA, USA, Ref. PA1-745), rabbit polyclonal anti-A2A R (1/100, ThermoFisher Scientific, Ref. PA1-042) and mouse monoclonal anti-σ1

(5) Proteomic Analysis of Cardioembolic and Large Artery Atherosclerotic Clots Using Reverse Phase Protein Array Technology Reveals Key Cellular Interactions Within Clot MicroenvironmentsCureusFebruary 22, 2021Mehdi Abbasi, Sean Fitzgerald, Jennifer Ayers-Ringler, Virginia Espina, Claudius Mueller, Sally Rucker, Ramanathan Kadirvel, David Kallmes, Waleed Brinjikji,Cell Signaling Technology,13333,1:100 "Cannabinoid receptor I (CNR1, CB1)",Cannabinoid receptor 1,Pierce,PA1-745,1:50 "Cannabinoid receptor II (CNR2, CB2)",Cannabinoid receptor 2,Pierce,PA1-746A,1:100 Collagen I,Collagen I

(6) Expression of cannabinoid CB₁ R-GPR55 heteromers in neuronal subtypes of the Macaca fascicularis striatumAnnals of the New York Academy of SciencesSeptember 1, 2020Martínez-Pinilla E, Rico AJ, Rivas-Santisteban R, Lillo J, Roda E, Navarro G, Franco R, Lanciego JL.

(7) Chemical Tools for Studying Lipid-Binding Class A G Protein-Coupled ReceptorsPharmacological reviewsJuly 1, 2017Cooper A, Singh S, Hook S, Tyndall JDA, Vernall AJ.2014). Flow cytometry has been used by Jean-Gilles et al. (2015) to quantify fluorescent antibody (PA1-745 and PA1-744; Affinity Bioreagents, Golden, CO) labeling of CB1 and CB2 receptors in the presence of

(8) Tumor-promoting effects of cannabinoid receptor type 1 in human melanoma cellsToxicology in vitro : an international journal published in association with BIBRAApril 1, 2017Carpi S, Fogli S, Polini B, Montagnani V, Podestà A, Breschi MC, Romanini A, Stecca B, Nieri P.

(9) Sex-dependent influence of chronic mild stress (CMS) on voluntary alcohol consumption; study of neurobiological consequencesPharmacology, biochemistry, and behaviorJanuary 1, 2017Marco EM, Ballesta JA, Irala C, Hernández MD, Serrano ME, Mela V, López-Gallardo M, Viveros MP.

(10) Microarray analysis of transcripts with elevated expressions in the rat medial or lateral habenula suggest fast GABAergic excitation in the medial habenula and habenular involvement in the regulation of feeding and energy balanceBrain structure & functionDecember 1, 2016Wagner F, Bernard R, Derst C, French L, Veh RW.

(11) Striatal adenosine-cannabinoid receptor interactions in rats over-expressing adenosine A2A receptorsJournal of neurochemistryMarch 1, 2016Chiodi V, Ferrante A, Ferraro L, Potenza RL, Armida M, Beggiato S, Pèzzola A, Bader M, Fuxe K, Popoli P, et al.

(12) Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic ExploitationPloS oneJanuary 1, 2016Freund P, Porpaczy EA, Le T, Gruber M, Pausz C, Staber P, Jäger U, Vanura K.antibodies The following cannabinoid receptor directed antibodies were tested: Anti-CB1 antibodies: Cat.No. PA1-745, Thermo Fisher Scientific Inc., Waltham, MA, USA; Cat.No. GTX100517, GeneTex Inc., Irvine, CA, USA;

(13) Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cellsActa physiologica (Oxford, England)May 1, 2015Jean-Gilles L, Braitch M, Latif ML, Aram J, Fahey AJ, Edwards LJ, Robins RA, Tanasescu R, Tighe PJ, Gran B, et al.FACS permeabilizing solution (BD Biosciences, Oxford, UK) and stained with antibodies CB1 [1 : 50] (PA1‐745), CB2 [1 : 50] (PA1‐744) (Affinity Bioreagents, Golden, CO, USA) or control normal rabbit IgG [1 : 40]

(14) Overexpression of cannabinoid CB2 receptor in the brain induces hyperglycaemia and a lean phenotype in adult miceJournal of neuroendocrinologyAugust 1, 2012Romero-Zerbo SY, Garcia-Gutierrez MS, Suárez J, Rivera P, Ruz-Maldonado I, Vida M, Rodriguez de Fonseca F, Manzanares J, Bermúdez-Silva FJ.

(15) Effects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signallingBritish journal of pharmacologyApril 1, 2012Oddi S, Dainese E, Sandiford S, Fezza F, Lanuti M, Chiurchiù V, Totaro A, Catanzaro G, Barcaroli D, De Laurenzi V, et al.

(16) Cannabinoid receptor 1 signaling in embryo neurodevelopmentBirth defects research. Part B, Developmental and reproductive toxicologyApril 1, 2012Psychoyos D, Vinod KY, Cao J, Xie S, Hyson RL, Wlodarczyk B, He W, Cooper TB, Hungund BL, Finnell RH.previously described (Psychoyos and Finnell, 2009a). The following primary antibodies we used: CB1 (PA1-745; Pierce-Antibodies; 1:200 dilution), DAGLα (sc-133308; Santa Cruz Biotechnology; 1:200) and En1 (Developmental

(17) Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's diseaseNeurobiology of diseaseMarch 1, 2012Chiodi V, Uchigashima M, Beggiato S, Ferrante A, Armida M, Martire A, Potenza RL, Ferraro L, Tanganelli S, Watanabe M, et al.

(18) CB1 and CB2 cannabinoid receptor expression during development and in epileptogenic developmental pathologiesNeuroscienceSeptember 29, 2010Zurolo E, Iyer AM, Spliet WG, Van Rijen PC, Troost D, Gorter JA, Aronica E.

(19) Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptorsPloS oneJanuary 14, 2010Cencioni MT, Chiurchiù V, Catanzaro G, Borsellino G, Bernardi G, Battistini L, Maccarrone M.

(20) Ulcerative colitis induces changes on the expression of the endocannabinoid system in the human colonic tissuePloS oneSeptember 4, 2009Marquéz L, Suárez J, Iglesias M, Bermudez-Silva FJ, Rodríguez de Fonseca F, Andreu M.

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Cannabinoid Receptor 1 Antibody from Thermo Fisher Scientific

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Cannabinoid Receptor 1 Antibody from Thermo Fisher Scientific

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