The Mouse Anti p53 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to Antigen NY-CO-13, bbl, LFS1, Mutant p53, TP53, and tumor protein p53. This antibody recognizes Human antigen. The Mouse Anti p53 Antibody has been shown to work in the following applications: Immunoprecipitation, and Western Blot.
Description
Description: Monoclonal antibodies are produced by immunizing mouse with full length His-tagged p53 protein.
Introduction: p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma