MOUSE ANTI RAT CD68 MCA341R from Bio-Rad (Formerly AbD Serotec)

Product Specs
ItemMOUSE ANTI RAT CD68
CompanyBio-Rad
Price $505.00Supplier Page View Company Product Page
Catalog NumberMCA341R
CloneED1
TargetCD68
HostMouse
FormatPurified IgG - liquid
Quantity0.25 mg
ApplicationsWestern Blotting,Immunohistology - Paraffin,Immunoprecipitation,Flow Cytometry,Immunohistology - Frozen,Immunofluorescence
IsotypeIgG1
ReactivityRat, Bovine
ClonalityMonoclonal Antibody
NCBI Full Gene NameCd68 molecule
ConcentrationIgG concentration 1.0 mg/ml

Questions and Answers

What species does this antibody work with, and in what contexts has it been used?

The Mouse Anti Rat CD68 antibody has been shown to work with both rat and bovine species. It has been utilized in various applications, including immunohistochemistry, where it has been employed to identify macrophages in rat brain tissue following ischemic stroke, as demonstrated in studies such as and .

Can this antibody be used for detecting macrophages in inflammatory conditions?

Yes, the Mouse Anti Rat CD68 antibody is specifically designed to identify macrophages, which are key players in inflammatory responses. It has been used in studies to assess macrophage infiltration in various models, including those of thermal injury and pulmonary fibrosis, as referenced in and .

How has this antibody been applied in research related to neuroinflammation?

The Mouse Anti Rat CD68 antibody has been effectively used to study neuroinflammation, particularly in the context of traumatic brain injury and ischemic stroke. For instance, it was utilized to evaluate microglial activation and macrophage presence in rat models, highlighting its role in the inflammatory response following brain injuries, as seen in and .

What is the recommended dilution for using this antibody in immunohistochemistry?

The Mouse Anti Rat CD68 antibody is typically used at a dilution of 1:500 for immunohistochemistry applications, as indicated in various studies, including and .

Bio-Rad

Bio-Rad Laboratories, Inc. Life Science Research Group 2000 Alfred Nobel Drive

Hercules, California 94547

United States

Phone: 800-424 6723
800-879 2289

Company Profile

Website: http://discover.bio-rad.com

(1) Search for Inhibitors against Inflammatory Responses of Microglia in a Meroterpenoid Library Constructed by Synthetic–Biological Manipulation of Biosynthetic PathwaysACS OmegaApril 7, 2026Kanako Takahashi, Zhiyang Quan, Yukari Shigemoto-Mogami, Bei-bei Zhang, Tomohiko Ohwada, Ikuro Abe, Takayoshi Awakawa, Kaoru Satoplastic wells and incubated with the primary antibodies (mouse anti-CD68 monoclonal antibody [1:100, MCA341R, Bio-Rad, Hercules, California, USA] and rabbit anti-Iba1 polyclonal antibody [1:500, 090–19741, FUJIFILM

(2) Differences on the Natural Course of Chronic Kidney Disease Progression, Induced by 5/6 Renal Ablation Model in Three Different Rat Stains: Wistar, Lewis, and Fischer 344Life (Basel)March 4, 2026Samuel de de Jesus, Paloma Souza Noda, Ana Laura Rubio Francini, Flavio Teles Filho, Mariana Matera Veras, Ane Claudia Fernandes Nunes, Irene de Lourdes Noronha, Camilla Fanelliimmunohistochemistry, with the specific antibodies anti-CD68 (Serotec (Bio-Rad Laboratories, Hercules, CA, USA), #MCA341R, diluted 1:200) and anti-PCNA (Proliferating Cell Nuclear Antigen, Dako (Dako, Glostrup, Denmark), #M0879

(3) EXPRESS: T Cells Modulate the Development and Maintenance of Painful Paclitaxel-Induced Peripheral Neuropathy in RNU RatsMolecular PainJanuary 14, 2026Ahmed Olalekan Bakare, Gerard Limerick, Vasudha Goel, Ratan K Banik, Lei Zheng, Andrew J Shepherd, Kristine Glunde, Qin Zheng, Eellan SivanesanInstitutes of Health, Bethesda, MD, USA). The primary antibodies used were mouse anti-CD68 (1:100; cat: MCA341R; Bio-Rad, Hercules, CA, USA), rabbit anti-CD206 (1:500; cat: AB64693; Abcam, Cambridge, UK), and rabbit

(4) Gestational stress disrupts the neuroimmune environment in the nucleus accumbens of maternal ratsBrain, Behavior, & Immunity - HealthDecember 1, 2025Courtney N. Dye, Dominic V. Franceschelli, Caitlin Goodpaster, Lynde M. Wangler, Amanda Ringland, Jonathan P. Godbout, Kathryn M. Lenz, Benedetta Leunercalcium binding adaptor molecule 1 (Iba1; Abcam [Ab107159]), cluster of differentiation 68 (CD68; Biorad [MCA341R]), and postsynaptic density 95 (PSD95; Abcam [Ab18258]). This tissue was used to assess the following

(5) Investigation into the use of a chitosan scaffold for tarsal plate substitution in eyelid reconstructionRegenerative BiomaterialsNovember 7, 2025Glyn Chidlow, John P M Wood, Luke A Halliday, Robert J Casson, Shaveen S B Gamage, Andrea J O’Connor, Dinesh Selva, Michelle T SunAntibody,Host,Dilution,Company,Catalogue α-SMA,Mouse,1:2000,Dako,M0851 CD206,Rabbit,"1:50,000",Abcam,ab64693 CD3,Rabbit,1:2500,Dako,A0452 Collagen IV,Rabbit,1:1000,Abcam,ab6586 Collagen V,Goat,1:1000,Chemicon,ab781 ED1,Mouse,1:500,Bio-Rad,MCA341R eNOS,Mouse,1:1000,BD Transduction,N30020 Iba1,Goat,1:5000,Novus Biologicals,NB100-1028 iNOS,Rabbit,1:500,BD

(6) Evaluation of proton minibeam radiation therapy on anti-tumor immune responses in a rat model of glioblastomaCancer Immunology ResearchNovember 3, 2025Lorea Iturri, Miriam Riquelme-Perez, Pierre-Emannuel Bonté, Sarah Potiron, Christel Goudot, Marjorie Juchaux, Elise Brisebard, Cristèle Gilbert, Julie Espenon, Ramón Ortiz, et al.FoxP3 (clone EPR22102-37, ab215206, Abcam, RRID: AB_2860568)] and three antibodies [CD68 (clone ED1, MCA341R, Bio-Rad, RRID: AB_2291300), CD8 (clone OX-8, ab33786, Abcam, RRID: AB_726709), and Pax5 (clone EPR3730(2),

(7) Biofabrication of 3D-printed, pre-cross-linked alginate dialdehyde–gelatin (ADA–GEL) scaffolds for an in vivo metastatic arteriovenous loop tumor modelFrontiers in Bioengineering and BiotechnologyNovember 3, 2025Evelin Sandor, Tannaz Karimi, Rafael Schmid, Yvonne Kulicke, Stefanie Heltmann-Meyer, Carolin Eckert, Sonja K. Schmidt, Jonas Röder, Markus V. Heppt, Aldo R. Boccaccini, et al.Erlangen. For macrophage staining, slides were incubated with a mouse monoclonal anti rat CD68 antibody (MCA341R, Bio-Rad, Hercules, CA, United States) at a dilution of 1: 20 in AB Diluent, yielding a final concentration

(8) Dual ROCK1/2–MYLK4 Kinase Inhibition Preserves Visual Function in a Rat Model of Neuromyelitis Optica Spectrum Disorder Optic NeuritisCellsOctober 31, 2025Chin-Te Huang, Monir Hossen, Tu-Wen Chen, Chih-Wei Fu, Yi-Hsun Chen, Tzu-Lun Huang, Rong-Kung Tsaimicroglia, diluted 1:100; Abcam, San Francisco, CA, USA), and CD68 (ED1 for macrophages, diluted 1:100; MCA341R; Bio-Rad, Hercules, CA, USA). Appropriate secondary antibodies were applied to the tissue samples for

(9) The Role of Cerebrolysin in Promoting Axonal Regeneration and Functional Recovery after Peripheral Nerve Injury: A Focus on Macrophage ActivationAdvanced Pharmaceutical BulletinOctober 11, 2025Aida Karimian, asadollah Abdolmaleki, Asadollah Abdolmaleki, Saber Zahri, Hussein A. A. Ghanimiwere incubated overnight at 4°C with primary antibodies: mouse anti-rat CD68 (1:100, IgG1; Bio-Rad, MCA341R) to label total macrophages, CD86 (1:100, IgG1; Bio-Rad, MCA2874) to detect M1 macrophages, and CD206

(10) SPAchips: Microparticles Used for the Selective In Vitro Labelling of MicrogliaInt J Mol SciOctober 8, 2025Justyna Gargas, Justyna Janowska, Beata Dabrowska-Bouta, Marta Sidoryk-Wegrzynowicz, Alberto M. Hernández-Pinto, Rubén Miguez, Teresa Suárez, Lidia Struzynska, Joanna Sypeckamicroglia/macrophages, including: OX42 (abcam, Cambridge, UK, ab1211; 1:200), ED1 (BioRad, Hercules, CA, USA, MCA341R; 1:400) and Iba1 (abcam ab107159; 1:400). OPC cultures were double labelled for oligodendrocyte lineage

(11) Potential of Heparan Sulphate Mimetics Integrated Into Collagen Scaffolds for Enhanced Skin Wound HealingWound Repair RegenOctober 7, 2025Nancy Avila-Martinez, Roman Krymchenko, Merel Gansevoort, Maren Pfirrmann, Sofia Aparicio, Agnes Choppin, Franck Chiappini, Denis Barritault, Martijn Verdoes, Toin H. van Kuppevelt, et al.visualize myofibroblasts and mature blood vessels and for cluster of differentiation 68 (CD68, 1:200, MCA341R, AbD Serotec) to study macrophages. Sections were deparaffinized and incubated with 0.5% hydrogen peroxide

(12) Quantitative temporal analysis of pancreatic islet T lymphocyte and macrophage infiltration heralded by serum IgE in congenic BioBreeding (BB) Gimap5-/- rats at risk for insulitis and acute onset diabetesInflamm ResOctober 3, 2025Josefine Jönsson, Linda Faxius, Jeanette Tångrot, Krysten Vance, Stephanie Jerman, Doug Bowman, Marika Bogdani, Peter Ericsson, Rasmus Bennet, Anita Ramelius, et al.440, 465, and 490 µm were stained for ED1, a macrophage marker (mouse anti-rat CD68, diluted 1:100, MCA341R, Bio-Rad, Hercules, CA, USA). Sections at depths of 10, 35, 60, 220, 245, 270, 430, 455, and 480 µm

(13) Immunological response and tissue loss in a rodent model of chronic traumatic brain injury treated with resolvinJ Inflamm (Lond)October 2, 2025Olivia Kiwanuka, Julie Cheung, Anders Hånell, Caroline Lindbladantibodies Anti-Iba1 (1:500, FUJIFILM Wako Pure Chemical Corporation, 019–19741), ED1/CD68 (1:1000, BIO-RAD, MCA341R), MPO (1:50, Jackson ImmunoResearch, GR325073-3), and CY3/CD3 (1:50, Jackson ImmunoResearch, GR293692-3). The

(14) Graphene oxide increases the phototransduction efficiency of copolymeric nanoimplants and rescues visual functions in rat and pig models of Retinitis pigmentosaNature CommunicationsSeptember 30, 2025F. Galluzzi, S. Francia, S. Cupini, T. Gianiorio, G. Mantero, M. L. DiFrancesco, T. Ravasenga, Jasnoor, M. Attanasio, J. F. Maya-Vetencourt, et al.Sigma-Aldrich), anti-Iba-1 (cat# 019-19741; 1:300; Fujifilm Wako, Neuss, Germany) and anti- rat CD68 (1:250, MCA341R, BioRad Antibodies), respectively. To remove the excess primary antibodies, samples were rinsed 3 times

(15) Low-intensity muscle contraction exercise reduces pain sensitivity by modulating peripheral pathology and spinal sensitization in end-stage knee osteoarthritis ratsFrontiers in Pain ResearchSeptember 29, 2025Satoko Motokawa, Junya Sakamoto, Ryo Sasaki, Yuki Nishi, Yuichiro Honda, Ayumi Takahashi, Minoru Okitaserum for 60 min. Next, the sections were incubated with a mouse anti-CD68 monoclonal antibody (Cat No. MCA341R, 1:200; Bio-Rad, Hercules, CA), rabbit anti-ITGAX/CD11c polyclonal antibody (Cat No. LS-B15988, 1:2,000;

(16) Sustained oxygen-releasing hydrogel implants enhance flap regeneration by promoting mitochondrial biogenesis under mild hypoxiaBioactive MaterialsSeptember 1, 2025Sungmi Jeon, Seol-Ha Jeong, Mi Hyun Lee, Jeong Wook Seo, Da-Seul Kim, Nicole Joy Bassous, Javier Alejandro Lozano Soto, Cholong Choi, Montserrat Legorreta Gonzalez, Elaine Belén Nolasco Díaz, et al.(HIF-1a, 1:400, 48085S, Cell signaling, Massachusetts, USA), Cluster of Differentiation 68(CD68, 1:250, MCA341R, Bio-rad, California, USA), Phospho-nuclear factor kappa-light-chain-enhancer of activated B cells p65

(17) Cardioprotective effects of extracellular vesicles from hypoxia-preconditioned mesenchymal stromal cells in experimental pulmonary arterial hypertensionStem Cell Res TherAugust 29, 2025Renata Trabach Santos, Cássia Lisboa Braga, Maria Eduarda de Sá Freire Onofre, Carla Medeiros da Silva, Nazareth de Novaes Rocha, Rodrigo Gonzaga Veras, Sabrina Sodré de Souza Serra, Douglas Esteves Teixeira, Sarah Aparecida dos Santos Alves, Beatriz Toja Miranda, et al.Carpinteria, CA, USA). Primary antibodies were incubated overnight at 4 °C: CD68 (1:50 dilution; Bio-Rad #MCA341R), mannose receptor (1:100 dilution; Abcam #ab64693), inducible nitric oxide synthase (iNOS; 1:100 dilution;

(18) Abstinence from cocaine self-administration promotes microglial pruning of astrocytes, which drives cocaine-seeking behaviorCell ReportsAugust 26, 2025Anze Testen, Jonathan W. VanRyzin, Tania J. Bellinger, Ronald Kim, Han Wang, Matthew J. Gastinger, Emily A. Witt, Janay P. Franklin, Haley A. Vecchiarelli, Katherine Picard, et al.,Thermo Fisher #MA1–045,RRID: AB325399 Rabbit anti-GFAP,Dako #Z0334,RRID: AB_10013382 Mouse anti-CD68,BioRad #MCA341R,RRID: AB_2291300 Rabbit anti-Iba1,Wako #019–19741,RRID: AB_839504 Chicken anti-C3,Abcam #ab48581,RRID:

(19) Modulation of epileptogenesis through transplantation of human mesenchymal stem cells with or without GDNF releaseCell Mol Life SciAugust 21, 2025Eliška Waloschková, Esbjörn Melin, Camille Baumlin, My Andersson, Alberto Martínez Serrano, Merab Kokaia, Marco Ledriin PBS containing 0.25% Triton-X and incubated with the primary antibody (1:200, CD68 antibody/ED1, MCA341R, Bio-Rad, Hercules, CA, USA/1:2000, anti-Cherry antibody, ab205402, Abcam, Cambridge, UK) overnight

(20) 3D-printed optogenetic neural probe integrated with microfluidic tube for opsin/drug deliverySci RepAugust 7, 2025Revathi Sukesan, Mohsin Mohammed, Keonghwan Oh, Malvika Sharma, Dipesh Chaudhury, Sohmyung Haincubation in primary antibody: i) mouse anti-CD68/ED1 (a marker for activated microglia, 1:250, Cat. Nr. MCA341R, Biorad, USA), ii) rabbit anti-glial fibrillary acidic protein (GFAP, an astrocytic cytoskeletal protein;

Be the First to Write a Review!

MOUSE ANTI RAT CD68

MOUSE ANTI RAT CD68

MOUSE ANTI RAT CD68 from Bio-Rad (Formerly AbD Serotec)

Questions and Answers

Bio-Rad

Citations (294)

Reviews

MOUSE ANTI RAT CD68 from Bio-Rad (Formerly AbD Serotec)

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map