Anti-Granzyme B GZMB Monoclonal Antibody M00353-1 from BosterBio

Product Specs
ItemAnti-Granzyme B GZMB Monoclonal Antibody
CompanyBosterBio
Price $370.00Supplier Page View Company Product Page
Catalog NumberM00353-1
Quantity100 µl/vial
ApplicationsIHC,ICC,IF,IP
FormatLiquid, Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required
ReactivityHuman
HostRabbit
ImmunogenA synthesized peptide derived from human Granzyme B This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis
NCBI Gene AliasesCSP-B, CTLA1, CGL1, CGL-1, CCPI, HLP, CTSGL1, SECT, C11, CSPB
ClonalityMonoclonal
PurityAffinity-chromatography
CloneAAHC-7
Concentration0.5mg/ml
Research AreaAdaptive Immunity,Apoptosis,Cell Biology,Immunology,Innate Immunity,NK Cells,T Cells
IsotypeIgG
StorageStore at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles
TargetGranzyme B
Gene NameGZMB
Molecular WeightObserved: 23 kDa
Calculated: 132494 MW
Antibody TypePrimary Antibodies