MyBioSource.com's Granzyme B Antibody is a Rabbit Polyclonal antibody. The Granzyme B Antibody was generated using CCPI, and GZMB as the antigen and it reacts with Human.
Description
Granzymes are exogenous serine proteases that are released by cytoplasmic granules within cytotoxic T-cells and natural killer cells. Their purpose is to induce apoptosis within virus-infected cells, thus destroying them. Anti-Granzyme B antibodies have been useful in diagnosing Natural Killer/T-cell Lymphoma, as well as Anaplastic Large Cell Lymphoma. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease