EGFR Antibody (DH8.3) [FITC] - Mutant
Product Image: EGFR Antibody (DH8.3) [FITC] - Mutant [NBP2-50599F] - Vial of FITC conjugated antibody. FITC is optimally excited at 498 nm by the Blue laser (488 nm) and has an emission maximum of 519 nm.
Supplier Page from Novus Biologicals, a Bio-Techne Brand for EGFR Antibody (DH8.3) [FITC] - Mutant
Available conjugates: Available conjugates: Janelia Fluor 525, Alexa Fluor 350, Janelia Fluor 669, FITC, DyLight 680, HRP, DyLight 755, PE/Cy7, Allophycocyanin, Biotin, DyLight 550, DyLight 405, PerCP, Alexa Fluor 405, DyLight 650, Janelia Fluor 646Specificity: Clone DH8.3 of EGF R/ErbB1 antibody is specific for Truncated EGFR which is also called EGFR type III, EGFRvIII or delta-EGFR (characterised by a deletion of 267 amino acids in the extracellular domain, leading to a receptor which is unable to bind ligand yet is constitutively active). Because of its impaired internalisation and degradation, EGFRvIII is known to enhance tumourigenesis. NOTE: Clone DH8.3 DOES NOT cross-react with full length or wildtype EGFR (wtEGFR).Sizes Available: 0.1 ml