EGFR Antibody (DH8.3) [PerCP] - Mutant NBP2-50599PCP from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemEGFR Antibody (DH8.3) [PerCP] - Mutant
CompanyNovus Biologicals, a Bio-Techne Brand
Price $529.00Supplier Page View Company Product Page
Catalog NumberNBP2-50599PCP
Quantity0.1 ml
ApplicationsFlow Cytometry,ELISA,Immunohistochemistry,Immunoprecipitation,Western Blot,CyTOF-ready
Conjugate/TagPerCP
PurityProtein G purified
ReactivityHuman
TargetEGFR
IsotypeIgG1
CloneDH8.3
HostMouse
ImmunogenSynthetic peptide corresponding to the junctional region of the truncated receptor LEEKKGNYVV TDHC,conju gated to keyhole limpet haemcyanin
ClonalityMonoclonal
Research AreaCancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
FormatPBS
Antibody TypePrimary Antibodies
StorageStore at 4C in the dark
NCBI Gene AliasesERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA
NCBI Full Gene Nameepidermal growth factor receptor

Specifications/Features

Available conjugates: Available conjugates: Janelia Fluor 525, DyLight 550, Janelia Fluor 669, PerCP

Specificity: Clone DH8.3 of EGF R/ErbB1 antibody is specific for Truncated EGFR which is also called EGFR type III, EGFRvIII or delta-EGFR (characterised by a deletion of 267 amino acids in the extracellular domain, leading to a receptor which is unable to bind ligand yet is constitutively active). Because of its impaired internalisation and degradation, EGFRvIII is known to enhance tumourigenesis. NOTE: Clone DH8.3 DOES NOT cross-react with full length or wildtype EGFR (wtEGFR).

Sizes Available: 0.1 ml

Add to Compare List