The Cingulin antibody from MyBioSource.com is a Mouse Monoclonal antibody to Cingulin, and Miscellaneous. This antibody recognizes Human, Mouse, Bovine, and Xenopus/Amphibian antigen. The Cingulin antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Mouse monoclonal Cingulin antibody
Cingulin is a protein that in humans is encoded by the CGN gene. Cingulin is specifically localized at tight junctions in epithelial cells, unlike ZO-1, which is also detected at adherens-type junctions in non-epithelial cells. During early Xenopus embryo development, cingulin is detected at a cortical localization, and then accumulates at apical junctions, unlike ZO-1 and other junctional proteins, that are targeted to the new regions of cell-cell contact via the lateral domain