The Mouse monoclonal antibody Anti-Human RUNX1 from MyBioSource.com is a Mouse Monoclonal antibody to AML1, RUNX1, and Transcription factor. This antibody recognizes Human antigen. The Mouse monoclonal antibody Anti-Human RUNX1 has been shown to work in the following applications: Dot Blot.
Description
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Two transcript variants encoding different isoforms have been found for this gene. [NCBI Entrez Gene Summary]