The Sp17 (C17) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. The Sp17 (C17) Antibody has been shown to work in the following applications: Western Blot.
Description
The highly immunogenic cancer-testis antigen Sp17 was originally thought to be expressed exclusively in the testis with the primary function of binding the extra cellular matrix of the oocyte (1.2). Upon further investigation Sp17 was found to be expressed by tumor cells with multiple myeloma in up to 30% of the cases studied (3.4). Sp17 has three functional domains. N-terminal. central. and C-terminal domains. The N-terminal domain contains an A-kinase anchoring protein binding motif. The central domain is necessary for heparin binding and the C-terminal domain contains a calmodulin-binding domain (1&2).