MyBioSource.com's c-Myc (C10) Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunoprecipitation, and Western Blot. The c-Myc (C10) Antibody was generated using CMyc, and MYC as the antigen and it reacts with Human.
Description
The transcription factor c-Myc is a proto-oncogene that is at the focal point in cell cycle regulation. metabolism. apoptosis. differentiation. cell adhesion. and tumorigenesis (1-3). In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated (2&3).c-Myc also plays a pivotal role in apoptosis. most notably its connections to the CD95/Fas death receptor pathway (1&4). These different biological responses to c-Myc are most likely the result of different overlapping subsets of c-Myc target genes (1).