Phospho-Met (Tyr1003) (13D11) Rabbit mAb 3135T from Cell Signaling Technology

Product Specs
ItemPhospho-Met (Tyr1003) (13D11) Rabbit mAb
CompanyCell Signaling Technology
Price $162.00 Inquire
Catalog Number3135T
Quantity20 µl
ApplicationsW
ReactivityH, M, R
TargetMet (Tyr1003) phosphate
IsotypeIgG
HostRabbit
NCBI Full Gene NameMET proto-oncogene, receptor tyrosine kinase
NCBI Gene AliasesAUTS9, DA11, DFNB97, HGFR, RCCP2, c-Met
ClonalityMonoclonal
Research AreaRTK
Molecular Weight145

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Autoregulation of the MET receptor tyrosine kinase by its intracellular juxtamembrane domainBiochem JDecember 17, 2025Edmond M. Linossi, Carla A. Espinoza, Gabriella O. Estevam, James S. Fraser, Natalia Juraimages from replicate experiments are included in Supplementary Data S1. Phosphorylation at MET Y1003 (#3135, CST) was also measured to confirm complete dephosphorylation of the recombinant MET protein (Supp Figure

(2) Autoregulation of the MET receptor tyrosine kinase by its intracellular juxtamembrane domainBiochem JDecember 17, 2025Edmond M. Linossi, Carla A. Espinoza, Gabriella O. Estevam, James S. Fraser, Natalia Juraimages from replicate experiments are included in Supplementary Data S1. Phosphorylation at MET Y1003 (#3135, CST) was also measured to confirm complete dephosphorylation of the recombinant MET protein (Supp Figure

(3) Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancersCell Reports MedicineAugust 19, 2025Madelaine S. Theardy, Mitsunobu Takeda, Alexey Sorokin, Shuaitong Chen, Zecheng Yang, Xiaofei Wang, Preeti Kanikarla, Oluwadara Coker, Phuoc Nguyen, Yongkun Wei, et al.Anti-phospho-EGFR (Cell Signaling Technology, 4407, 1:1000 for WB); Anti-MET (Cell Signaling Technology, 3135, 1:1000 for WB); Anti-phospho-MET (Cell Signaling Technology, 3135, 1:1000 for WB); Anti-HER2/ErB2 (Cell Signaling Technology

(4) KRAS-mutant non-small cell lung cancer (NSCLC) therapy based on tepotinib and omeprazole combinationCell Communication and SignalingJune 12, 2024Rafael Rosell, Eloisa Jantus-Lewintre, Peng Cao, Xueting Cai, Baojuan Xing, Masaoki Ito, Jose Luis Gomez-Vazquez, Mireia Marco-Jordán, Silvia Calabuig-Fariñas, Andrés Felipe Cardona, et al.Cell Signaling), Phospho-MET (Tyr1234/1235) (D26) (#3077, Cell Signaling), phospho-MET (Tyr1003) (13D11) (#3135, Cell Signaling), phospho-Akt (Ser473) (#9271, Cell Signaling), phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204)

(5) Dimer Interface in Natural Variant NK1 Is Dispensable for HGF-Dependent Met Receptor ActivationInternational journal of molecular sciencesAugust 26, 2021Tahira Y, Sakai K, Sato H, Imamura R, Matsumoto K.SDS-PAGE and Western blotting. Anti-pMet (Y1234/1235; #3077S), -pMet (Y1349; #3133S), -pMet (Y1003; #3135), -Met (#8198S), -pGab1 (Y627; #3233S), -Gab (#3232S), -pAKT (S473; #4060S), -AKT (#9272S), -pErk (T202/Y204;

(6) Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screeningNature communicationsSeptember 5, 2019Kim M, Mun H, Sung CO, Cho EJ, Jeon HJ, Chun SM, Jung DJ, Shin TH, Jeong GS, Kim DK, et al.milk in 1X TBST were incubated overnight at 4 °C: anti-phosphorylated Met (pMet; 1:1000 dilutions, #3135, Cell Signaling Technology), Met (1:1000 dilutions, #4560, Cell Signaling Technology), phosphorylated

(7) The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistanceAutophagyJuly 1, 2019Huang X, Gan G, Wang X, Xu T, Xie W.immunoprecipitation; Alphamab Co. Ltd, 5D5, for therapy), anti-p-MET Y1003 (Cell Signaling Technology, 3135), anti-p-MET Y1234/1235 (Cell Signaling Technology, 3077, for WB and immunohistochemistry [IHC]), anti-p-MET

(8) Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancerNature communicationsJune 20, 2019Jin N, Bi A, Lan X, Xu J, Wang X, Liu Y, Wang T, Tang S, Zeng H, Chen Z, et al.following antibodies were used: FGFR1 (9740 S), p-EGFR Tyr1068 (3777 S), EGFR (4267 S), p-MET Tyr1003 (3135 S), MET (8198 S), p-RET Tyr905 (3221 S), RET (3223 S), p-AKT Ser473 (4060 L), AKT (4691 S), p-ERK1/2

(9) MET-targeting antibody (emibetuzumab) and kinase inhibitor (merestinib) as single agent or in combination in a cancer model bearing MET exon 14 skippingInvestigational New DrugsAugust 1, 2018S. Betty Yan, Suzane L. Um, Victoria L. Peek, Jennifer R. Stephens, Wei Zeng, Bruce W. Konicek, Ling Liu, Jason R. Manro, Volker Wacheck, Richard A. Walgren(clone D1C2) (Cat #8198), p-MET (Y1234/1235) (clone D26) (Cat #3077), p-MET (Y1003) (clone 13D11) (Cat #3135), EGFR (clone D38B1) (Cat #4267), pEGFR (Y1068) (clone D7A5) (Cat #3777), ERK1/2 (clone L34F12) (Cat

(10) El Principio de la PrimacÃa de la Realidad como Garante de los Derechos Laborales de los Trabajadores Oficiales Vinculados Mediante Contratos de PrestaciÃ³n de ServiciosVerba lurisJune 30, 2018MarÃa Amparo CortÃ©s Moralesaplicable El régimen aplicable a los trabajadores oficiales se encuentra establecido en los Decretos 3135 de 1968 y 1848 de 1969, asimismo, en las disposiciones que en materia colectiva establezca el CST. En

(11) La fuerza mayor como antemperaciÃ³n del carÃ¡cter sancionatorio de la caducidad: un posible antÃdoto al curare de la puesta en marcha de la pretensiÃ³n contencioso/administrativaTemas Socio-JurÃdicosJuly 23, 2017JuliÃ¡n SuÃ¡rez BohÃ³rquezfenómenos de la prescripción trienal prevista en los arts. 488 del CST, 151 del CPT y SS, 41 del D. 3135/1968 y 102 de 1848/1969, y el de la caducidad de las acciones consagrada en el art. 136 del anterior

(12) Activating Mutations in PIK3CA Lead to Widespread Modulation of the Tyrosine PhosphoproteomeJournal of proteome researchSeptember 4, 2015Zahari MS, Wu X, Blair BG, Pinto SM, Nirujogi RS, Jelinek CA, Malhotra R, Kim MS, Park BH, Pandey A.(12677; Cell Signaling Technology), anti-EPHA2 (6997; Cell Signaling Technology), antiphospho-MET Y1003 (3135; Cell Signaling Technology), anti-MET (3148; Cell Signaling Technology), antiphospho-EFNB1 Y324 (OAAF00520;

(13) EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 functionProceedings of the National Academy of Sciences of the United States of AmericaJuly 21, 2015Phuchareon J, McCormick F, Eisele DW, Tetsu O.Cell Signaling Technology), IGF1Rβ (3018, Cell Signaling Technology), phospho-Tyr1003, Tyr1234/1235, and Tyr1349 Met (3135, 3077, and 3133; Cell Signaling Technology), Met (3127, Cell Signaling Technology), phospho-Thy239/240

(14) Hepatocyte growth factor regulates the TGF-β1-induced proliferation, differentiation and secretory function of cardiac fibroblastsInternational Journal of Molecular MedicineAugust 1, 2014XIN YI, XIAOYAN LI, YANLI ZHOU, SHAN REN, WEIGUO WAN, GAOKE FENG, XUEJUN JIANGphospho-ERK1/2Thr202/Thr204 (no. 4370); phospho-AktThr308 (no. 13038); Akt (no. 9272); phospho-c-MetTyr1003 (no. 3135); c-Met (no. 3127); phospho- Smad2Ser465/467 (no. 3101); Smad2 (no. 5339); phospho- Smad3Ser423/425

(15) Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signalingBloodMarch 6, 2014Mleczko-Sanecka K, Roche F, da Silva AR, Call D, D'Alessio F, Ragab A, Lapinski PE, Ummanni R, Korf U, Oakes C, et al.No Company 4EBP1 ADAM10 bCatenin BRAF caveolin_1 CBL Claudin-3 COL4A3BP CREB Cyclin_D1 Cyclin_E E2F1 EGFR EIF4B ERBB2 ERK1_ERK2 FIH GLI1 GLI2 GLI3 GRB2 GSK3A GSK3B HIF1A HSP70 HSP90 Ikbalpha IntegrinB3 JNK1 Ki67 LKB1 MEK1 MNK1 mTOR c-MYC NME1/NDKA NMYC non-phospho-bCatentin NOTCH2 NOTCH3 NUMB p38 p4EBP1_T3746 p70S6K PAK1 PAK2 pAKT_S473 pAKT_T308 PARP pbCatenin_S33_S37_T41 pBRAF_Ser445 pcJUN_S63 PCNA pcRAF_S259 pCREB_Ser133 PDK1 pEGFR_Y1068 pEGFR_Y1173 pEGFR_Y845 pEIF4B_S406 pEIF4B_S422 pERBB2_Y1139 pERBB2_Y1248 pERBB2_Y877 pERBB3_Y1197 pERBB3_Y1289 pERK1_pERK2_T202_Y204 pFOXO1/3a_T24/32 pFOXO1_S319/pFOXO4_S262 pFOXO3a_S253 pFOXO3a_S318/321 pGSK3A_S21 pGSK3B_S9 PI3K_p110 PI3K_p85 pJNK_T183_Y185 PKCa PLCg pLKB1_Ser428 pMEK_S217_S221 pMET_Y1003 pMSK1_S376 pmTOR_S2448 pNFkB_S276 pNFkB_S536 PP2A PP2B 9644 ab1997 4718 HPA028185 2772 9562 2876 2764 9434 9665 9502 ab32577 2747 9112 610142 sc-177 DP155-05 9664 HPA035645 9197 1495-1 2926 sc-427 3742 4065 2646 3592 AB-17 06-182 4426 2534 sc-28674 HPA005534 3972 9338 9315 3716 4872 CA1023 9242 4702 610628 M7240 3050 5453 610122 2195 2972 1472-1 5353 sc-53993 5665 4530 5276 2761 sc397 610241 9212 2855 sc-126 611261 2602 2247-1 9271 9275 AM30 3079 9561 2696 558036 sc-7907 9421 9198 3062 2236 4407 2231 5399 3591 ab53290 ab47755 2241 4561 4791 4370 9464 2487 CST Abcam CST HPA CST CST CST CST CST CST CST Abcam CST CST BD SantaCruz Acris CST HPA CST Epitomics CST SantaCruz CST CST CST CST Neomarkers Millipore CST CST SantaCruz HPA CST CST CST CST CST Novagen CST CST BD DAKO CST CST BD CST CST Epitomics CST SantaCruz Millipore CST CST CST SantaCruz BD CST CST SantaCruz BD CST CST CST CST Calbiochem CST CST CST BD SantaCruz CST CST CST CST CST CST CST CST Abcam Abcam CST CST CST CST CST CST pp38_T180_Y182 pp70S6K_T389 pp70S6K_T421_S424 pPAK1_S144_S141 pPAK2_S20 pPDK1_S241 pPKCa_S657 pPLCg_S1248 pPRAS40_T246 pPTEN_T366_S370 PRAS40 pRPS6_S235_S236 pRPS6_S240_S244 pSRC_Y416 PTCH PTEN PTPN6 pTSC2 RhoA ROCK1 ROCK2 RPS6 RPS6KA1 SHH SHP2 SNAIL SRC SUFU TSC1 TSC2 9466 9465 9316 9323 ab32569 ab40755 44-682G ab32376 ab41433 3482 M7683 3135 9591 2971 3037 3033 2039 4953 9215 9286 9289 9206 1135-1 2606 1609-1 2607 3061 06-822 4510 2997 CST CST CST CST Abcam Abcam Invitrogen Abcam Abcam CST Sigma CST CST CST CST CST CST CST CST CST CST CST Epitomics CST Epitomics CST CST Millipore CST CST Table

(16) Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid TumorsCell reportsJanuary 1, 0001"Oberlick EM, Rees MG, Seashore-Ludlow B, Vazquez F, Nelson GM, Dharia NV, Weir BA, Tsherniak A, Ghandi M, Krill-Burger JM, et al."AB_2221302 Gab1,Cell Signaling,Cat#3232; RRID: AB_2304999 p-Met (Tyr1003) (13D11),Cell Signaling,Cat#3135; RRID: AB_2285325 p-MET (Tyr1234/1235) (D26) XP,Cell Signaling,Cat#3077; RRID: AB_2143884 p-MET (Tyr1349)

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Phospho-Met (Tyr1003) (13D11) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-Met (Tyr1003) (13D11) Rabbit mAb from Cell Signaling Technology

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