Cell Cycle/Checkpoint Antibody Sampler Kit 9917T from Cell Signaling Technology

Description

Phospho-cdc2 (Tyr15) (10A11) Rabbit mAb detects endogenous levels of cdc2 protein only when phosphorylated at tyrosine 15. Based on sequence similarity, the antibody may cross-react with CDK2 and CDK3. Phospho-Chk2 (Thr68) (C13C1) Rabbit mAb detects endogenous levels of Chk2 only when phosphorylated at Thr68. Phospho-Chk1 (Ser345) Antibody detects Chk1 only when phosphorylated at Ser345 and does not cross-react with other proteins. Phospho-Rb (Ser795) Antibody detects Rb only when phosphorylated at Ser795 and does not cross-react with Rb phosphorylated at other sites. Phospho-Rb (Ser807/811) (D20B12) XP® Rabbit mAb recognizes endogenous levels of Rb protein only when phosphorylated at Ser807, Ser811, or at both sites. This antibody does not cross-react with Rb phosphorylated at Ser608. Phospho-p53 (Ser15) (16G8) Mouse mAb detects endogenous levels of p53 only when phosphorylated at Ser15. The antibody does not cross-react with p53 phosphorylated at other sites

Product Specs
ItemCell Cycle/Checkpoint Antibody Sampler Kit
CompanyCell Signaling Technology
Price $558.00 Inquire
Catalog Number9917T
Quantity1 Kit
Targetp53 (Ser15) phosphate;Rb (Ser795) phosphate;Rb (Ser807/Ser811) phosphate;Chk2 (Thr68) phosphate;Cdc2 (Tyr15) phosphate;Mouse IgG;Chk1 (Ser345) phosphate
Research AreaCell Cycle / Checkpoint Control
NCBI Full Gene Namecyclin dependent kinase 1, RB transcriptional corepressor 1, checkpoint kinase 2, tumor protein p53, checkpoint kinase 1
NCBI Gene AliasesBMFS5, PPP1R130, p110-RB1, HuCds1, BCC7, CDC2, pp110, RB, p105-Rb, P53, PP1425, TRP53, hCds1, CDC28A, pRb, CDS1, LFS1, CHK1, CHK2, RAD53, LFS2, P34CDC2, OSRC

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Disrupted Lipid Metabolism, Cytokine Signaling, and Dormancy: Hallmarks of Doxorubicin-Resistant Triple-Negative Breast Cancer ModelsCancers (Basel)December 23, 2024Radhakrishnan Vishnubalaji, Nehad M. Alajezusing primary and secondary antibodies from the Cell Cycle/Checkpoint Antibody Sampler Kit (cat. no. 9917, Cell Signaling Technology, Boston, MA, USA). Membranes were visualized using SuperSignal™ West Femto

(2) Knockdown of mitochondrial threonyl-tRNA synthetase 2 inhibits lung adenocarcinoma cell proliferation and induces apoptosisBioengineeredMarch 1, 2022Tian H, Yan H, Zhang Y, Fu Q, Li C, He J, Li H, Zhou Y, Huang Y, Li R.(15,067-1-AP, Proteintech, China); GAPDH (60,004-1-Ig, Proteintech, China); Phospho-RB (ser807/811) (9917, Cell Signaling Technology); Cyclin E1(20,808, Cell Signaling Technology); Cyclin E2 (4132, Cell Signaling Technology

(3) Gene expression profile of cancer stem‑like cells in the SW480 colon adenocarcinoma cell lineOncology reportsJuly 1, 2019Wang Y, Zhou L, Qing Q, Li Y, Li L, Dong X, Xiao B.p‑CDC2, p‑p53, p‑CHEK1, p‑CHEK2, p‑retinoblastoma 1 (Rb1) and p‑Rb2 (all from the same kit; cat. no. 9917) (all dilutions, 1:1,000; all from Cell Signaling Technology, Inc., Danvers, MA, USA), and β‑actin and

(4) Apatinib enhances the radiosensitivity of the esophageal cancer cell line KYSE‑150 by inducing apoptosis and cell cycle redistributionOncology LettersDecember 6, 2018Lijun Hu et al.Cell Signaling Technology, Inc., Danvers, MA, USA); anti-phospho-serine/threonine-protein kinase-2 (pCHK2; catalog no. 9917; 1:1,000; Cell Signaling Technology, Inc.); and anti-VEGFR-2 (catalog no. 2472; 1:1,000; Cell Signaling Technology

(5) Therapeutic potential of thalidomide for gemcitabine-resistant bladder cancerInternational Journal of OncologyNovember 1, 2015YEN TA HUANG, CHUAN CHU CHENG, TED H. CHIU, PEI CHUN LAI(no. 2775), cell cycle regulation (no. 9932), and cell cycle/checkpoint antibody sampler kits (no. 9917); Abcam (Cambridge, MA, USA), anti-securin (ab3305) and anti-cleaved PARP [poly (ADP-ribose) polymerase,

(6) Therapeutic potential of sepantronium bromide YM155 in gemcitabine-resistant human urothelial carcinoma cellsOncology ReportsFebruary 1, 2014YEN TA HUANG, CHUAN CHU CHENG, TZU CHUN LIN, TED H. CHIU, PEI CHUN LAIanti-LC3B (#2775), cell cycle regulation (#9932) and cell cycle/checkpoint antibody sampler kits (#9917), Abcam (Cambridge, MA, USA) with anti-securin (ab3305), GeneTex, (Irvine, CA, USA) with anti-bcl2 (GTX127958),

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Cancers (Basel)

Cell Cycle/Checkpoint Antibody Sampler Kit from Cell Signaling Technology

Description

Cell Signaling Technology

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Cell Cycle/Checkpoint Antibody Sampler Kit from Cell Signaling Technology

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