OTOF Antibody PA5-52935 from Thermo Fisher Scientific

Product Specs
ItemOTOF Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-52935
Quantity100 µL
ApplicationsImmunohistochemistry (Paraffin)
Concentration0.1 mg/mL
Conjugate/TagUnconjugated
FormatPBS with 40% glycerol and 0.02% sodium azide; pH 7.2
ReactivityHuman
TargetOTOF
IsotypeIgG
HostRabbit
ImmunogenRecombinant protein corresponding to Human OTOF. Recombinant protein control fragment (Product #RP-90139)
NCBI Full Gene Nameotoferlin
NCBI Gene AliasesAUNB1, DFNB6, DFNB9, FER1L2, NSRD9
ClonalityPolyclonal
PurityAntigen affinity chromatography
Antibody TypePrimary
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles

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United States

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Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Human promoter-driven AAV tools enable precision gene therapy targeting cochlear hair cellsCell Reports MedicineApril 21, 2026Liyan Zhang, Yicheng Lu, Xianmin Wu, Jinyi Fan, Xinru Zhang, Yang Xu, Hao Wei, Qiuhan Sun, Lulu Jiang, Huawei Tuo, et al.anti-Sox2 (goat, R&D systems, Cat#AF2018), Anti-Otoferlin (C-terminal, rabbit, Thermo Scientific, Cat#PA552935), Anti-Otoferlin (N-terminal, mouse, Abcam, Cat#ab53233), and anti-HA (rat, Roche, Cat#11867423001)

(2) Hair cell-specific Myo15 promoter-mediated gene therapy rescues hearing in DFNB9 mouse modelMolecular therapy. Nucleic acidsMarch 12, 2024Wang H, Xun M, Tang H, Zhao J, Hu S, Zhang L, Lv J, Wang D, Chen Y, Liu J, et al.mouse IgG1 anti-otoferlin (1:200 dilution; ab53233; Abcam), rabbit IgG anti-otoferlin (1:200 dilution; PA5-52935; Invitrogen), and mouse IgG1 anti-CtBP2 (1:200 dilution; 612044; BD BioSciences). The following secondary

(3) AAV-Mediated Gene Therapy Restores Hearing in Patients with DFNB9 DeafnessAdvanced science (Weinheim, Baden-Wurttemberg, Germany)March 1, 2024Qi J, Tan F, Zhang L, Lu L, Zhang S, Zhai Y, Lu Y, Qian X, Dong W, Zhou Y, et al.antibodies were against OTOF‐N (Abcam, 1:200 dilution, ab53233), OTOF‐C (Invitrogen, 1:200 dilution, PA552935), and Phalloidin (Invitrogen, 1:1000 dilution, A22287). Confocal images were captured on a Zeiss LSM900. Inner

(4) Preclinical Efficacy And Safety Evaluation of AAV-OTOF in DFNB9 Mouse Model And Nonhuman PrimateAdvanced science (Weinheim, Baden-Wurttemberg, Germany)January 1, 2024Qi J, Zhang L, Tan F, Zhang Y, Zhou Y, Zhang Z, Wang H, Yu C, Jiang L, Liu J, et al.antibodies against Myosin7a (Proteus Bioscience, 256 790), OTOF‐N (Abcam, ab53233), OTOF‐C (Thermo fisher, PA552935), Sox2 (R&D systems, AF2018), Ctbp2 (Biosciences, 612 044), and GluR2 (Millipore, MAB397) were added

(5) Engineering of the AAV-Compatible Hair Cell-Specific Small-Size Myo15 Promoter for Gene Therapy in the Inner EarResearch (Washington, D.C.)January 1, 2024Hu SW, Lv J, Wang Z, Tang H, Wang H, Wang F, Wang D, Zhang J, Zhang L, Cao Q, et al.anti-otoferlin (N terminus from mouse immunoglobulin G1 (IgG1), ab53233, 1:200, Abcam; C terminus from rabbit, PA552935, 1:200 dilution, Invitrogen) was used to test the recombinant efficiency of otoferlin in HCs after injecting

(6) Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primatesMolecular therapy. Methods & clinical developmentDecember 14, 2023Zhang L, Wang H, Xun M, Tang H, Wang J, Lv J, Zhu B, Chen Y, Wang D, Hu S, et al.with the primary antibodies rabbit immunoglobulin G (IgG) anti-OTOF (1:2,000 dilution, catalog no. PA5-52935, Thermo Fisher Scientific), rabbit IgG anti-glyceraldehyde 3-phosphate dehydrogenase (1:1,000 dilution,

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OTOF Antibody from Thermo Fisher Scientific

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OTOF Antibody from Thermo Fisher Scientific

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