Fig 1: Immunohistochemical staining of the TUNEL and cleaved Caspase-3 positive cells in the hippocampus. A) TUNEL-positive cells in SGZ and DG were stained dark brown and were shown with an arrow. B) Positive cell number in 1000 µm2 in SGZ was shown in the graph. C) Positive cell number in 1000 µm2 in DG was shown in the graph. The graph was expressed as the means ± SD. *P<0.05 Control vs MetS-MetS+Ins, and #P<0.05 MetS+Ins vs MetS. D) Cleaved Caspase-3 positive cells in SGZ and DG were stained dark brown and shown with arrow. E) Positive cell number in 1000 µm2 in SGZ was shown in the graph. F) Positive cell number in 1000 µm2 in DG was shown in the graph