CD8a Antibody Alexa Fluor 700 56-0088-42 from Thermo Fisher Scientific

Product Specs
ItemCD8a Antibody Alexa Fluor 700
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog Number56-0088-42
Storage4°C, store in dark, DO NOT FREEZE!
Antibody TypePrimary
Storage Temperature4° C, store in dark, DO NOT FREEZE!
PurityAffinity chromatography
ReactivityHuman (Hu)
ClonalityMonoclonal
NCBI Gene AliasesLY3, CD8alpha, CD8beta, Leu2, CD8B1, p32, LEU2, Ly-3, CD8, P37, LYT3
NCBI Full Gene NameCD8 subunit beta, CD8 subunit alpha
ApplicationsFlow Cytometry (FCM)
HostMouse
CloneRPA-T8
IsotypeIgG1 kappa
TargetCD8a
FormatPBS with BSA and 0.09% sodium azide; pH 7.2
Conjugate/TagAlexa Fluor™ 700
Concentration5 µL/Test
Quantity100 Tests

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Thermo Fisher Scientific

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Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Disruption of metabolic licensing by JAK inhibitors constrains CD8 T cell activation and effector functionCell Death & DiseaseMarch 24, 2026Luisina Inés Onofrio, Carolina Abrate, Ingrid Strusberg, Liliana Morales, Danilo Guillermo Ceschin, Carolina Lucía Montes, Cinthia Carolina Stempin, Eva Acosta Rodríguezanti-CD8 (PerCP, UCHT-4, ImmunoTools, Cat: 21620085; or Alexa Fluor 700, RPA-T8, eBioscience, Cat: 56-0088-42), anti-CD45RA (FITC, ALB11, Beckman Coulter, Cat: A07786; or PE-Cy7, 5H9, BD, Cat: 561216), and anti-CCR7

(2) Pyruvate Kinase M2 activation reprograms mitochondria in CD8 T cells enhancing effector functions and anti-tumor efficacy of anti-PD1 therapyCell MetabolismJune 3, 2025Seyedeh Sahar Mortazavi Farsani, Jignesh Soni, Lu Jin, Anil Kumar Yadav, Shivani Bansal, Tian Mi, Leena Hilakivi-Clarke, Robert Clarke, Benjamin Youngblood, Amrita Cheema, et al.CD90,STEMCELL,"Clone OX-7, Cat#60024AD" Anti human Alexa Fluor700-CD8,Invitrogen,"Clone: RPA-T8, Cat# 56-0088-42" Anti human APC-IFNγ,Invitrogen,"Clone: 4S.B3, Cat# 17-7319-82" Anti human BUV395-CD45RA,Invitrogen,"Clone:

(3) Dopamine D2 receptor agonists abrogate neuroendocrine tumour angiogenesis to inhibit chemotherapy-refractory small cell lung cancer progressionCell Death DisMay 9, 2025Sk. Kayum Alam, Anuradha Pandit, Li Wang, Seyedeh Sahar Mortazavi Farsani, Britteny A. Thiele, Parvathy Manoj, Marie Christine Aubry, Vivek Verma, Charles M. Rudin, Ying-Chun Lo, et al.°C for 30 min. Following centrifugation, primary antibodies (anti-human CD8, eBioscience, cat no.: 56-0088-42; anti-human granzyme B-PE, BD Pharmigen, cat no.: 12889642; anti-human PD-1-FITC, BD Pharmigen, cat

(4) Kynurenine promotes the immune escape of colorectal cancer cells via NAT10-mediated ac4C acetylation of PD-L1Clinics (Sao Paulo)April 16, 2025Zaibiao Wang, Manman Yin, Ruhang Zhou, Ming Li, Jie Peng, Zhengguang Wanganti-human CD4 (Cat. #11–0049–42; Thermo Fisher) and Phycoerythrin (PE)-conjugated anti-human CD8 (Cat. #56–0088–42; Thermo Fisher) antibodies at 4 °C for 30 min. The suspensions were then washed with sheath fluid. Flow cytometry

(5) Protocol for isolation of tumor-derived extracellular vesicles and functional studies on human T cell subsetsSTAR protocolsJune 21, 2024Swatler J, Targońska A, Turos-Korgul L, Mosieniak G, Piwocka K.

(6) Mucosal prime-boost immunization with live murine pneumonia virus-vectored SARS-CoV-2 vaccine is protective in macaquesNature communicationsApril 26, 2024Kaiser JA, Nelson CE, Liu X, Park HS, Matsuoka Y, Luongo C, Santos C, Ahlers LRH, Herbert R, Moore IN, et al.

(7) Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapyCell reports. MedicineMarch 19, 2024St Paul M, Saibil SD, Kates M, Han S, Lien SC, Laister RC, Hezaveh K, Kloetgen A, Penny S, Guo T, et al.

(8) Immune response induced by standard and fractional doses of 17DD yellow fever vaccineNPJ vaccinesMarch 8, 2024Abdala-Torres T, Campi-Azevedo AC, da Silva-Pereira RA, Dos Santos LI, Henriques PM, Costa-Rocha IA, Otta DA, Peruhype-Magalhães V, Teixeira-Carvalho A, Araújo MSS, et al.1:100, Cat #: 562658), anti-CD8-Alexa Fluor 700 (eBioscience, clone RPA-T8, dilution: 5:100, Cat #: 56-0088-42), anti-CD45RO-BV421 (BD, clone UCHL1, dilution: 1:100, Cat #: 562641), anti-CD27-APC-H7 (BD, clone M-T271,

(9) Crohn's disease treatment and memory T-cell subset changes: insights from a case seriesTranslational gastroenterology and hepatologyJanuary 1, 2024Chen ZH, Tang YY, Sheng SY, Lu CG, Xu KW, Chen GJ, Wang YF, Gu Y, Song XM, Hong H.anti-human CD4-Percp.Cy5.5 (cat. 560650, RPA-T4; BD Biosciences), anti-human CD8-Alexa Fluor 700 (cat. 56-0088-42, RPA-T8; eBioscience), anti-human CCR7-PE.eFluor610 (cat. 61-1979-42, 3D12; eBioscience), anti-human

(10) TCR ligand potency differentially impacts PD-1 inhibitory effects on diverse signaling pathwaysThe Journal of experimental medicineDecember 4, 2023Chan W, Cao YM, Zhao X, Schrom EC, Jia D, Song J, Sibener LV, Dong S, Fernandes RA, Bradfield CJ, et al.

(11) Rethinking IL-1 Antagonism in Respiratory Viral Infections: A Role for IL-1 Signaling in the Development of Antiviral T Cell ImmunityInternational journal of molecular sciencesOctober 30, 2023Van Den Eeckhout B, Ballegeer M, De Clercq J, Burg E, Saelens X, Vandekerckhove L, Gerlo S.

(12) Prostate cancer cells synergistically defend against CD8(+) T cells by secreting exosomal PD-L1Cancer medicineAugust 1, 2023Li D, Zhou X, Xu W, Chen Y, Mu C, Zhao X, Yang T, Wang G, Wei L, Ma B.

(13) Soluble NKG2D ligands impair CD8(+) T cell antitumor function dependent of NKG2D downregulation in neuroblastomaOncology lettersJuly 1, 2023Zhang Y, Luo F, Dong K.

(14) Endosialin-positive tumor-derived pericytes promote tumor progression through impeding the infiltration of CD8(+) T cells in clear cell renal cell carcinomaCancer immunology, immunotherapy : CIIJune 1, 2023Lu T, Zhang J, Lu S, Yang F, Gan L, Wu X, Song H, Liu S, Xu C, Han D, et al.

(15) PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cellsNature communicationsDecember 12, 2022Li Q, Zhang L, You W, Xu J, Dai J, Hua D, Zhang R, Yao F, Zhou S, Huang W, et al.

(16) VLA-4 suppression by senescence signals regulates meningeal immunity and leptomeningeal metastasiseLifeDecember 9, 2022Li J, Huang D, Lei B, Huang J, Yang L, Nie M, Su S, Zhao Q, Wang Y.

(17) Screening of an individualized treatment strategy for an advanced gallbladder cancer using patient-derived tumor xenograft and organoid modelsFrontiers in oncologyJanuary 1, 2022Tan D, An J, Gong M, Wang H, Li H, Meng H, Zhang C, Zhao Y, Ge X, Shi C.

(18) Multipeptide stimulated PBMCs generate T(EM)/T(CM) for adoptive cell therapy in multiple myelomaOncotargetSeptember 28, 2021Vardam-Kaur T, Pathangey LB, McCormick DJ, Bergsagel PL, Cohen PA, Gendler SJ.

(19) In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of plasma viremiaNature communicationsJune 17, 2021Cole B, Lambrechts L, Gantner P, Noppe Y, Bonine N, Witkowski W, Chen L, Palmer S, Mullins JI, Chomont N, et al.

(20) Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomesNature communicationsMay 21, 2021Renner K, Schwittay T, Chaabane S, Gottschling J, Müller C, Tiefenböck C, Salewski JN, Winter F, Buchtler S, Balam S, et al.

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CD8a Antibody Alexa Fluor 700 from Thermo Fisher Scientific

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CD8a Antibody Alexa Fluor 700 from Thermo Fisher Scientific

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