Mouse IgG2a kappa PE Isotype Control 12-4724-82 from Thermo Fisher Scientific

Product Specs
ItemMouse IgG2a kappa PE Isotype Control
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog Number12-4724-82
Quantity100 µg
ApplicationsControl, Flow Cytometry
Concentration0.2 mg/mL
Conjugate/TagPE
FormatPBS with 0.09% sodium azide; pH 7.2
TargetMouse IgG2a kappa
IsotypeIgG2a kappa
CloneeBM2a
HostMouse
Antibody TypeIsotype Control
Storage4°C, store in dark, DO NOT FREEZE!
ClonalityMonoclonal
PurityAffinity chromatography
Storage Temperature4° C, store in dark, DO NOT FREEZE!

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Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

Company Profile

Website: www.thermofisher.com

(1) MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancerCell reports. MedicineJuly 15, 2025Del Rey-Vergara R, Galindo-Campos MA, Rocha P, Carpes M, Martínez C, Masfarré L, Menéndez S, Quimis F, Rossell A, Iñañez A, et al.Thermo Fisher Scientific), MHC class I-PE (#12-5958-82; RRID:AB_10598797; Thermo Fisher Scientific; 1:100; isotype control: #12-4724-82; RRID:AB_470064; Thermo Fisher Scientific), PD-L1-APC (#17-5982-82; RRID:AB_2688092; Thermo Fisher Scientific;

(2) Conditionally replicative adenovirus as a therapy for malignant peripheral nerve sheath tumorsMol Ther OncolJune 20, 2024Nikrad JA, Galvin RT, Sheehy MM, Novacek EL, Jacobsen KL, Corbière SMAS, Beckmann PJ, Jubenville TA, Yamamoto M, Largaespada DA.anti-MHC Class I H-2Kb (eBioscience, 12-5958-80) or PE mouse IgG2a kappa isotype control (eBioscience, 12-4724-82) was performed on 1 × 106 cells isolated with non-enzymatic dissociation (Sigma-Aldrich, C5789). For

(3) CTLA-4 expression on CD4(+) lymphocytes in patients with sepsis-associated immunosuppression and its relationship to mTOR mediated autophagic-lysosomal disorderFrontiers in immunologyJanuary 1, 2024Cheng W, Zhang J, Li D, Lei X, Wang H, Cui N.CD152 (CTLA-4) Monoclonal Antibody (14D3), PE, eBioscience™ Invitrogen 12-1529-42; Mouse IgG2a kappa Isotype Control (eBM2a), PE, eBioscience™ Invitrogen 12-4724-82). To measure intracellular cytokines in CD4+ T cells following ex vivo stimulation, cells were first

(4) 3D printed PLGA/MgO/PDA composite scaffold by low-temperature deposition manufacturing for bone tissue engineering applicationsRegenerative therapyDecember 1, 2023Tan L, Ye Z, Zhuang W, Mao B, Li H, Li X, Wu J, Sang H.Mouse IgG1 Isotype Control (11711) [Alexa Fluor® 488] (IC002G, Novus Biologicals), Mouse IgG2a kappa Isotype Control (eBM2a) [PE] (12-4724-82, eBioscience™) and Mouse IgG1 kappa Isotype Control (P3.6.2.8.1) [FITC] (11-4714-81, eBioscience™). 2.11

(5) Inflammasome activation under high cholesterol load triggers a protective microglial phenotype while promoting neuronal pyroptosisTranslational neurodegenerationMarch 9, 2023de Dios C, Abadin X, Roca-Agujetas V, Jimenez-Martinez M, Morales A, Trullas R, Mari M, Colell A.12–9856-42, RRID: AB_2572749) and the corresponding IgG2a-PE isotype control (Thermo Fisher Scientific, 12-4724-82, RRID: AB_470064) (dilution 1:20) for 20 min at 4 °C. Then, cells were washed with 3 ml PBS and finally

(6) Amanita muscaria extract potentiates production of proinflammatory cytokines by dsRNA-activated human microgliaFrontiers in pharmacologyJanuary 1, 2023Wagner A, Pehar M, Yan Z, Kulka M.PBS for 1 h at 4°C. Cells were labelled with isotypes (IgG1-PE (568275, BD Biosciences), IgG2a-PE (12–4724–82, Invitrogen), IgG2a-APC (553932, BD Biosciences), or IgG2a-FITC (sc-2856, Santa Cruz Biotechnology Inc.)

(7) Changes in circulating exosome molecular profiles following surgery/(chemo)radiotherapy: early detection of response in head and neck cancer patientsBritish journal of cancerDecember 1, 2021Theodoraki MN, Laban S, Jackson EK, Lotfi R, Schuler PJ, Brunner C, Hoffmann TK, Whiteside TL, Hofmann L.(12-0037-42, RRID:AB_1272078), anti-mouse-IgG1-PE (12-4714-42, RRID: AB_1944423) and anti-mouse-IgG2a-PE (12-4724-82, RRID:AB_470064) from eBioscience (San Diego, CA, USA); anti-CTLA-4-APC (349908, RRID:AB_10679122) and

(8) Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenzaiScienceOctober 22, 2021Shibuya M, Tamiya S, Kawai A, Hirai T, Cragg MS, Yoshioka Y.AT130-2),Invitrogen,Cat# 12-0321-82;RRID: AB_2572557 PE mouse IgG2a κ isotype control (clone: eBM2a),Invitrogen,Cat# 12-4724-82;RRID: AB_470064 PE anti-mouse FcγRIII (CD16; clone: 275003),R&D Systems,Cat# FAB19601P-100RRID: AB_2246942 PE

(9) Effects of Extracellular Vesicles from Blood-Derived Products on Osteoarthritic Chondrocytes within an Inflammation ModelInternational journal of molecular sciencesJuly 5, 2021Otahal A, Kramer K, Kuten-Pella O, Moser LB, Neubauer M, Lacza Z, Nehrer S, De Luna A.Krefeld, Germany, #A07764) or 1 μL PE-conjugated IgG2a kappa isotype control (Thermo Fisher Scientific, #12-4724-82) and kept for 30 min in the dark at RT. After adding 300 μL stain buffer, fluorescence was detected

(10) Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injuryCell death & diseaseApril 7, 2021Stark K, Goncharov T, Varfolomeev E, Xie L, Ngu H, Peng I, Anderson KR, Verschueren E, Choi M, Kirkpatrick DS, et al.IgG2b kappa isotype control, FITC (#11-4732-81, AB_763658); mouse IgG2a kappa isotype control, PE (#12-4724-82, AB_470064); mouse IgG1 kappa isotype control, Super Bright 600 (#63-4714-82, AB_2637448); mouse IgM

(11) JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemiasGenes & developmentJune 1, 2018Kim SK, Knight DA, Jones LR, Vervoort S, Ng AP, Seymour JF, Bradner JE, Waibel M, Kats L, Johnstone RW.a negative control for IL7R (IgG1-PECy7; BD Biosciences, 557872) and CRLF2 (IgG2a-PE; eBioscience, 12-4724-82). Histology Leukemia-infiltrated livers and spleens from mice were resected and fixed in 10% neutral-buffered

(12) High-density lipoprotein suppresses tumor necrosis factor alpha production by mycobacteria-infected human macrophagesScientific reportsApril 30, 2018Inoue M, Niki M, Ozeki Y, Nagi S, Chadeka EA, Yamaguchi T, Osada-Oka M, Ono K, Oda T, Mwende F, et al.

(13) Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in ChildrenFrontiers in immunologyJanuary 1, 2018Siebert JN, Hamann L, Verolet CM, Gameiro C, Grillet S, Siegrist CA, Posfay-Barbe KM.

(14) Innate inflammatory gene expression profiling in potential brain-dead donors: detailed investigation of the effect of common corticosteroid therapyInnate immunityJuly 1, 2017Gholamnezhadjafari R, Tajik N, Falak R, Aflatoonian R, Dehghan S, Rezaei A.

(15) Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B CellsPLoS pathogensJuly 1, 2016Frenkel D, Zhang F, Guirnalda P, Haynes C, Bockstal V, Radwanska M, Magez S, Black SJ.

(16) Guanine-Rich Sequences Are a Dominant Feature of Exosomal microRNAs across the Mammalian Species and Cell TypesPloS oneJanuary 1, 2016Momose F, Seo N, Akahori Y, Sawada S, Harada N, Ogura T, Akiyoshi K, Shiku H.

(17) Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitisThe Journal of clinical investigationNovember 2, 2015Millet A, Martin KR, Bonnefoy F, Saas P, Mocek J, Alkan M, Terrier B, Kerstein A, Tamassia N, Satyanarayanan SK, et al.

(18) Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8⁺ T-cell responses and immune memoryOncoimmunologyApril 1, 2015Wu J, Waxman DJ.

(19) The COP II adaptor protein TMED7 is required to initiate and mediate the delivery of TLR4 to the plasma membraneScience signalingJuly 29, 2014Liaunardy-Jopeace A, Bryant CE, Gay NJ.

(20) Biologically active polymers from spontaneous carotenoid oxidation: a new frontier in carotenoid activityPloS oneJanuary 1, 2014Johnston JB, Nickerson JG, Daroszewski J, Mogg TJ, Burton GW.