CD4 Antibody Functional Grade 16-0049-85 from Thermo Fisher Scientific

Product Specs
ItemCD4 Antibody Functional Grade
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog Number16-0049-85
Quantity500 µg
ApplicationsFlow Cytometry, Functional assay, Neutralization
Concentration1 mg/mL
Conjugate/TagFunctional Grade
FormatPBS with no preservative; pH 7.2
ReactivityHuman
TargetCD4
IsotypeIgG1 kappa
CloneRPA-T4
HostMouse
NCBI Full Gene NameCD4 molecule
NCBI Gene AliasesCD4mut, IMD79, Leu-3, OKT4D, T4
ClonalityMonoclonal
PurityAffinity chromatography
Storage Temperature4° C
Antibody TypePrimary
Storage4°C

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Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

Company Profile

Website: www.thermofisher.com

(1) Modi-2 a vaccine stimulating CD4 responses to homocitrullinated self epitopes as therapy for solid cancersnpj VaccinesNovember 27, 2024Abdullah A. Al-Omari, Katherine W. Cook, Peter Symonds, Anne Skinner, Alissa Wright, Yaling Zhu, Vincent L. Coble, Omar J. Mohammed, Ruhul H. Choudhury, Nazim Uddin, et al.InVivoPlus + ), anti-CD4 (GK1.5, Cat #: BP0003-1, InVivoPlus + ) or anti-human CD4 (RPA-TA, Invitrogen, 16-0049-85) antibodies were added to appropriate wells for blocking studies. After incubation, captured IFNγ was

(2) IL-4 activates ULK1/Atg9a/Rab9 in asthma, NLRP3 inflammasomes, and Golgi fragmentation by increasing autophagy flux and mitochondrial oxidative stressRedox biologyMay 1, 2024Xu C, Song Y, Liu W, Liu R, Bai Q, Li L, Wang C, Yan G.

(3) Paediatric sepsis survivors are resistant to sepsis-induced long-term immune dysfunctionBritish journal of pharmacologyApril 1, 2024Colón DF, Wanderley CW, Turato WM, Borges VF, Franchin M, Castanheira FVS, Nascimento D, Prado D, Haruo Fernandes de Lima M, Volpon LC, et al.

(4) Myeloid‑derived suppressor cell accumulation induces Treg expansion and modulates lung malignancy progressionBiomedical reportsApril 1, 2024Wan Y, Mu X, Zhao J, Li L, Xu W, Zhang M.

(5) HLA-class II restricted TCR targeting human papillomavirus type 18 E7 induces solid tumor remission in miceNature communicationsMarch 13, 2024Long J, Chen X, He M, Ou S, Zhao Y, Yan Q, Ma M, Chen J, Qin X, Zhou X, et al.

(6) miR-539-5p targets BMP2 to regulate Treg activation in B-cell acute lymphoblastic leukemia through TGF-β/Smads/MAPKExperimental biology and medicine (Maywood, N.J.)January 1, 2024Dai Q, Shi R, Zhang G, Wang Y, Ye L, Peng L, Guo S, He J, Yang H, Jiang Y.

(7) Cathepsin S inhibition in dendritic cells prevents Th17 cell differentiation in perivascular adipose tissues following vascular injury in diabetic ratsJournal of biochemical and molecular toxicologySeptember 1, 2023Peng H, Lv Y, Li C, Cheng Z, He S, Wang C, Liu J.

(8) Rapamycin improves Graves' orbitopathy by suppressing CD4+ cytotoxic T lymphocytesJCI insightFebruary 8, 2023Zhang M, Chong KK, Chen ZY, Guo H, Liu YF, Kang YY, Li YJ, Shi TT, Lai KK, He MQ, et al.

(9) Dynamics of humoral and cellular response to three doses of anti-SARS-CoV-2 BNT162b2 vaccine in patients with hematological malignancies and older subjectsFrontiers in immunologyJanuary 1, 2023Laquintana V, Mottini C, Marchesi F, Marcozzi B, Terrenato I, Sperandio E, de Latouliere L, Carrieri F, Pimpinelli F, Pontone M, et al.

(10) Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunityNature communicationsDecember 10, 2022McEvoy CM, Murphy JM, Zhang L, Clotet-Freixas S, Mathews JA, An J, Karimzadeh M, Pouyabahar D, Su S, Zaslaver O, et al.

(11) Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 ReceptorCellsAugust 19, 2022Rode AKO, Buus TB, Mraz V, Al-Jaberi FAH, Lopez DV, Ford SL, Hennen S, Eliasen IP, Klewe IV, Gharehdaghi L, et al.

(12) Decoding the pathogenesis of Diamond-Blackfan anemia using single-cell RNA-seqCell discoveryMay 10, 2022Wang B, Wang C, Wan Y, Gao J, Ma Y, Zhang Y, Tong J, Zhang Y, Liu J, Chang L, et al.

(13) Single-cell RNA sequencing reveals the molecular features of peripheral blood immune cells in children, adults and centenariansFrontiers in immunologyJanuary 1, 2022Zhong J, Ding R, Jiang H, Li L, Wan J, Feng X, Chen M, Peng L, Li X, Lin J, et al.

(14) Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cellsMolecular therapy. Methods & clinical developmentSeptember 10, 2021Kierkels GJJ, van Diest E, Hernández-López P, Scheper W, de Bruin ACM, Frijlink E, Aarts-Riemens T, van Dooremalen SFJ, Beringer DX, Oostvogels R, et al.

(15) Murlentamab, a Low Fucosylated Anti-Müllerian Hormone Type II Receptor (AMHRII) Antibody, Exhibits Anti-Tumor Activity through Tumor-Associated Macrophage Reprogrammation and T Cell ActivationCancersApril 13, 2021Prat M, Salon M, Allain T, Dubreuil O, Noël G, Preisser L, Jean B, Cassard L, Lemée F, Tabah-Fish I, et al.

(16) Effects of the Antidiabetic Drugs Evogliptin and Sitagliptin on the Immune Function of CD26/DPP4 in Th1 CellsBiomolecules & therapeuticsMarch 1, 2021Yoon H, Sung JH, Song MJ.

(17) Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF InhibitionFrontiers in immunologyJanuary 1, 2021Yeku OO, Rao TD, Laster I, Kononenko A, Purdon TJ, Wang P, Cui Z, Liu H, Brentjens RJ, Spriggs D.

(18) Metabolism of short-chain fatty acid propionate induces surface expression of NKG2D ligands on cancer cellsFASEB journal : official publication of the Federation of American Societies for Experimental BiologyNovember 1, 2020Høgh RI, Møller SH, Jepsen SD, Mellergaard M, Lund A, Pejtersen M, Fitzner E, Andresen L, Skov S.

(19) Staphylococcus aureus induces cell-surface expression of immune stimulatory NKG2D ligands on human monocytesThe Journal of biological chemistryAugust 14, 2020Mellergaard M, Høgh RI, Lund A, Aldana BI, Guérillot R, Møller SH, Hayes AS, Panagiotopoulou N, Frimand Z, Jepsen SD, et al.

(20) Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic painThe Journal of international medical researchJuly 1, 2020He J, Xu Y, Yi M, Gu C, Zhu Y, Hu G.

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CD4 Antibody Functional Grade from Thermo Fisher Scientific

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CD4 Antibody Functional Grade from Thermo Fisher Scientific

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