LDL Receptor / LDLR Antibody (APC), Rabbit MAb from Sino Biological, Inc.

Yes, the LDL Receptor / LDLR Antibody (APC) has been shown to work in flow cytometry applications, as indicated by its usage in scientific literature. It is specifically designed for this application, allowing for the detection of LDL receptors in human cells.

This antibody is relevant in studies of hypercholesterolemia because it targets the LDL receptor, which plays a crucial role in cholesterol metabolism. Research, such as that by Fang et al. (2024), highlights the importance of LDLR in the efficacy of therapies aimed at reducing cholesterol levels, making this antibody valuable for investigating LDLR-related mechanisms in hypercholesterolemia.

While the specific usage of this antibody in animal models is not detailed, the LDL receptor is a key player in atherosclerosis research. The antibody's application in flow cytometry can facilitate the analysis of LDLR expression in various cell types, which is critical for understanding atherosclerosis in animal models.

The antibody is provided in a PBS solution containing 0.5% BSA and 0.03% ProClin300, which is suitable for maintaining sample integrity during flow cytometry. It is advisable to follow standard protocols for cell preparation and staining to ensure optimal results.