PE/Cyanine7 anti-mouse CD4 100421 from BioLegend

Product Specs
ItemPE/Cyanine7 anti-mouse CD4
CompanyBioLegend
Price $88.00Supplier Page View Company Product Page
Catalog Number100421
NCBI Gene AliasesL3T4, Ly-4
IsotypeRat IgG2b, kappa
HostRat
Quantity25 µg
Conjugate/TagPE/Cyanine7
ApplicationsFC - Quality tested
ReactivityMouse
CloneGK1.5
Antibody TypePrimary
NCBI Full Gene NameCD4 antigen
Concentration0.2mg/ml
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
ImmunogenMouse CTL clone V4
ClonalityMonoclonal
TargetCD4

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) SLC16A3-Induced Lactate Remodeling Drives Immune Evasion in Clear Cell Renal Cell Carcinoma via an Autocrine GPR81-ERK-c-MYC Feedback LoopBalkan Medical JournalJuly 31, 2026Shidong Zuo, Jinkai Dong, Yuhao Dong, Chengwei Fu, Xuechao Li, Baobo Zhao, Lu Wang, Yongjie Zhang, Lingsheng Kong, Tao Yang, et al.103138), PerCP/Cyanine5.5 anti-mouse CD3 (BioLegend, 100218), PE/Cyanine7 anti-mouse CD4 (BioLegend, 100422), Brilliant Violet 421 anti-mouse CD25 (BioLegend, 102033), Foxp3/Transcription Factor Staining Buffer

(2) A miniaturized-tumor culture platform for developing anti-tumor immunotherapiesTheranosticsJuly 13, 2026Yangyang Feng, Ling Li, Josh Haipeng Lei, Yuzhong Peng, Lijian Wang, Heng Sun, Dongyang Tang, Xinyu Guo, Xiangpeng Chu, Yunfeng Qiao, et al.BioLegend), CD45-Brilliant Violet 421 (103133, BioLegend), CD3-FITC (100204, BioLegend), CD4-PE/Cy7 (100422, BioLegend), CD8-PerCP/eFluor 710 (46-0081-82, Invitrogen), CD44-Alexa Fluor 700 (103026, BioLegend),

(3) Aging increases ovarian cancer growth, metastasis, and immunosuppression that can be alleviated by inhibiting hedgehog signalingbioRxivJuly 1, 2026Asha Kumari, Mohamed Halaby Elbahoty, Resha Rajkarnikar, Khushi Sureja, Manan Virendra Nayyar, Mehri Monavarian, Liz Macias Quintero, Katherine Fuh, Daniel J Tyrrell, Lalita A Shevde, et al.(147709, Biolegend), PerCP 5.5 -labeled anti-mouse CD3 (100218,Biolegend), PE/Cy7-labeled anti-mouse CD4 (100422, Biolegend), APC-labeled anti-mouse CD25 (102012, Biolegend), and PE-labeled anti-mouse Foxp3 (126403,

(4) Interleukin-10 at the crossroads of immunity in TLR7-induced lupusFrontiers in ImmunologyJune 22, 2026Johanna Pauline Williams, Anaïs Amend, Anna-Lena Schäfer, Paola Fernanda Ruiz-Aparicio, Antoine Nicolas Kraemer, Aileen Qian Luo, Laura Riechert, Lara Weber, Baerbel Keller, Rudolf Armin Manz, et al.12-3172-82), Anti-mouse CD4 Brilliant Violett 711 (BioLegend, 100549), Anti-mouse CD4 PE-Cyanine7 (BioLegend, 100421), Anti-mouse CD44 PE (BioLegend, 103023), Anti-mouse CD45 APC-Cyanine7 (BioLegend, 103116), Anti-mouse

(5) Fungal metabolite-based immunotherapy overcomes tumor-associated macrophage immunosuppressionCell Reports MedicineJune 16, 2026Jing Hu, Xiaoman Ju, Biping Deng, Kaicheng Tang, Dongchen Yuan, Xiaofan Sun, Lingmei Kong, Yixin Xu, Zhuo Fu, Stephane Koda, et al.53–6.7),BioLegend,Cat # 100708; RRID: AB_312747 PEcy7 Anti-mouse CD4 (Clone 53–6.7),BioLegend,Cat # 100422; RRID: AB_312707 PE Anti-mouse Granzyme B (Clone QA16A02),BioLegend,Cat # 372207; RRID: AB_2687031 Anti-mouse

(6) Anti-MOG IgG in EAE models clinical aspects of pediatric MOGADFrontiers in ImmunologyJune 15, 2026Yike Jiang, Estefany Y. Reyes, Elliot YH. Lin, Emily C. Troutman, Miranda Lumbreras, Devon T. DiPalma, Heather Van Mater, Mari L. ShinoharaAntigen,Fluorophore,Concentration,Company,Clone,Cat CD11b,BV605,1:400,BioLegend,M1/70,101257 CD16/32,BV421,1:200,BioLegend,93,101331 CD16/32,APC-Cy7,1:400,BioLegend,93,101327 CD19,PE,1:500,BioLegend,6D5,115508 CD4,APC-Cy7,1:500,BioLegend,GK1.5,100414 CD4,PE-Cy7,1:200,BioLegend,GK1.5,100422 CD45,BUV395,1:200,BD Biosciences,30-F11,564279 CD8α,PE-Cy5,1:500,BD Biosciences,53-6.7,553034 CD8α,APC-Cy7,1:200,BioLegend,53-6.7,100714 IFNγ,AF488,1:200,BioLegend,XMG1.2,505813 IgG1,APC,1:200,BioLegend,RMG1-1,406609 IL-17A,PE,1:200,BioLegend,TC11-18H10.1,506904 Ly6C,BV711,1:500,BioLegend,HK1.4,128037 Ly6G,AF700,1:500,BioLegend,1A8,127622 NK1.1,PE-Cy7,1:500,BioLegend,PK136,108714 TCRβ,FITC,1:500,BioLegend,H57-597,109205 TCRβ,PE-Cy5,1:200,BioLegend,H57-597,109210

(7) Biomimetic self-assembled copper nanoadjuvant potentiates hepatocellular carcinoma immunotherapy via cuproptosis-driven cGAS-STING activationMater Today BioJune 10, 2026Linhao Jing, Shuaijun Zhao, Chenguang Sun, Fangfang Cui, Yaning Xia, Yupeng Shi, Weijie Wang109813, Biolegend), FITC anti-mouse CD3ε (1:50, 100305, Biolegend), PE/Cyanine7 anti-mouse CD4 (1:100, 100421, Biolegend), PE/Cyanine5 anti-mouse CD8a (1:100, 100709, Biolegend), FITC anti-mouse/human CD11b (1:50,

(8) PLSCR3 Deficiency Triggers mtDNA-Driven cGAS-STING Activation to Potentiate Antitumor Immunity in Colorectal CancerHum MutatMay 25, 2026Limian Ling, Jingyu Wu, Lei Bao, Zhaohui Liu, Qun Deng, Xiaowen Ji, Shaojun Yu, Feng Yu, Akao Zhu, Qian Xiao, et al.553063), antimouse CD4 FITC (RM4‐5, BD Pharmingen, 553046), antimouse CD4 PE/Cy7 (GK1.5, BioLegend, 100421), antimouse CD8 FITC (53‐6.7, BD Pharmingen, 553031), and antimouse CD8a APC/Cy7 (53‐6.7, BioLegend,

(9) Peroxisomal ABCD1 deficiency in mice drives Th1 bias through 25-HC–LXR signaling in CD4+ T cellsFrontiers in ImmunologyMay 20, 2026Reina Maeda, Mayu Oishi, Ryutaro Nagamori, Mari Hikosaka-Kuniishi, Shiro Watanabe, Jung-Bum Lee, Masashi Morita, Takanori SoAPC-anti-IFN-γ (XMG1.2, 505809), PE-anti-CD8α (53-6.7, 100707), and PE/Cyanine7-anti-mouse CD4 (clone GK1.5, 100421) antibodies were obtained from BioLegend (San Diego, CA, U.S.A.). Isotype control antibodies, including

(10) Nano-granulated zoledronate sensitizes innate immune metabolism to enhance vaccine-induced and antitumor immunityCell Reports MedicineMay 19, 2026Meifang Chen, Xiaojia Jiao, Zhicheng Yan, Yueheng Wang, Jing Zhang, Qinghua Wu, Minghui Li, Shumin Fan, Yuan Wang, Wenbing Dai, et al.PE anti-mouse CD8a,Biolegend,Cat # 100707; RRID: AB_312746 PE/Cyanine7 anti-mouse CD4,Biolegend,Cat # 100421; RRID: AB_312706 PE/Cyanine7 anti-mouse CD11c,Biolegend,Cat # 117317; RRID: AB_493569 PE/Dazzle™ 594 anti-mouse/human CD11b

(11) Mesoporous bioactive glass–recombinant collagen III nanocomposite capsule promotes skin wound healing via adaptive immune modulationRegenerative BiomaterialsMay 9, 2026Yi Luo, Jian Jin, Wei Ding, Haihang Li, Xiujie Zhu, Minjia Yuan, Shihui Zhu, Wenxing Wang, Yixin Zhangstained with fluorochrome-conjugated antibodies against Ly6G (BioLegend, #108406), CD4 (BioLegend, #100422), CD8 (BioLegend, #100714), IL-13 (BioLegend, #501913), granzyme B (BioLegend, #515403), CD86 (BioLegend,

(12) Inhibition of protein kinase CK2 remodels the tumor immune microenvironment and sensitizes lung cancer to PD-L1 blockadeExperimental Hematology & OncologyMay 9, 2026Sijia Zhang, Lihua Luo, Yangang Qu, Yan Zong, Leichong Chen, Qianwen Li, Zhenyu Li, Jian Wang, Xiaohua Jie, Yun Xia, et al.(FITC, clone 17A2, BioLegend, Cat. No. 100203), CD4 (PE/Cyanine7, clone GK1.5, BioLegend, Cat. No. 100422), CD8a (Alexa Fluor 647, clone 53 − 6.7, BioLegend, Cat. No. 100724), PD-1 (CD279) (Brilliant Violet

(13) Females experience a greater benefit from surgical resection in an immune-dependent manner in a preclinical glioblastoma modelNeurooncol AdvMay 4, 2026Josephine Volovetz, Andrea Alvarez-Vazquez, Juyeun Lee, Ellen S Hong, Quinn T Ostrom, Christine Ann Pittman Ballard, Sina Ahmadi, Andrew Kurlich, Sabrina Z Wang, Kristen E Kay, et al.Cat# 125224), MHCII (BioLegend, Cat# 107606), NK1.1 (BioLegend, Cat# 108716), CD4 (BioLegend, Cat# 100422), CD8 (BioLegend, Cat# 100712), CD206 (BioLegend, Cat# 141712), Lyg6C (BioLegend, Cat# 128024), CD68

(14) Chronic stress disrupts hepatic homeostasis and accelerates liver cancer progression through ADRB2 signalingSci AdvMay 1, 2026Huimin Qin, Liuwei Chu, Xiaying Zheng, Huimei Zhang, Yue Lan, Ji Hu, Lu Li(BioLegend, 109838), CD8a-BV650 (BioLegend, 100742), CD4–phycoerythrin (PE)/cyanine 7 (Cy7) (BioLegend, 100421), NK1.1-allophycocyanin (APC)/Cy7 (BioLegend, 108723), CD45R/B220-phycoerythrin (PE) (BioLegend, 103207),

(15) Cuproptosis and Disulfidptosis Converge to Empower PD‐L1 Checkpoint Therapy via Cadict‐Induced PD‐L1 TranslationAdvanced ScienceMay 1, 2026Shaoqing Huang, Shiyao Song, Xinhua Zhang, Jialing Gao, Ruihan Pu, Jiatong Dai, Xiaoxue Wu, Lulu Chen, Qinghai Li, Xiaoting Liu, et al.(BioLegend, #103112, #103139), anti‐mouse CD3 (BioLegend, #100222, #100236), anti‐mouse CD4 (BioLegend, #100422, #100406), anti‐mouse CD8 (BioLegend, #100708, #100706), anti‐mouse IFN‐γ (BioLegend, #505808), and

(16) Cationic nanoparticles with disrupting neutrophil extracellular traps inhibit the progression of head and neck squamous cell carcinomaFrontiers in Cell and Developmental BiologyApril 22, 2026Zhaoqiang Zhang, Yujie Kang, Bingxu Lu, Guichao Zhang, Baohan Xie, Yunyi WangAlexa Fluor 700 anti-mouse CD3 (Catalog No. 100216, BioLegend), PE/Cyanine7 anti-mouse CD4 (Catalog No. 100422, BioLegend), APC anti-mouse CD25 Antibody (Catalog No. 102011, BioLegend), PE anti-mouse CD8a Antibody

(17) The CHI3L1-neutrophil axis drives immune suppression and breast cancer metastatic disseminationJCI InsightMarch 23, 2026Tarek Taifour, Adéline Massé, Yu Gu, Virginie Sanguin-Gendreau, Dongmei Zuo, Bin Xiao, Emilie Solymoss, Yunyun Shen, Hailey Proud, Sherif Samer Attalla, et al.65-0866-14), CD45 (BD Biosciences 564225), CD3 (BioLegend 100204), CD8 (BioLegend 100747), CD4 (BioLegend 100422), PD-1 (BioLegend 135221), CD44 (BioLegend 103008), F4/80 (BioLegend 123114), Ly6c (BioLegend 128046),

(18) Activating mutations in ESR1 contribute to an immunosuppressive breast tumor microenvironment by dampening cytokine secretionJCI InsightMarch 9, 2026Yu Gu, Dongmei Zuo, Qi-Xin Hu, Virginie Sanguin-Gendreau, Alain Pacis, Marie-Christine Guiot, Alexander Chih-Chieh Chang, Tarek Taifour, Chen Ling, Adrian V. Lee, et al.(ThermoFisher, 65-0866-14, 1:1000), CD45 (BD, 564225, 1:500), CD3 (BioLegend, 100204, 1:200), CD4 (BioLegend, 100422, 1:300), CD8 (BioLegend, 100748, 1:300), IFN-γ (BioLegend, 505808, 1:400), granzyme B (BioLegend, 515408,

(19) A STING signaling relay from tumor cells to macrophages mediates the improved efficacy of combination chemotherapy in pancreatic cancerJ Biomed SciMarch 4, 2026Honglu Ding, Yize Mao, Zehui Yao, Kaili Xing, Qiuxia Yang, Ruiqi Wang, Jun Wang, Yongxiang Liu, Hui Guo, Zining Wang, et al.Brilliant Violet 421™ anti-mouse CD45 (103134, Biolegend), APC anti-mouse CD3 (100236, Biolegend), PE/Cyanine7 anti-mouse CD4 (100422, Biolegend), FITC anti-mouse CD8a (100705, Biolegend), PerCP/Cyanine5.5 anti-mouse/human CD11b (101228,

(20) Collagen-Bearing Exosomes from Breast Cancer–Associated Fibroblasts Promote T-cell DysfunctionCancer Res CommunMarch 1, 2026Samir Jana, Matthew Lawton, Pin-Ji Lei, Harold Hui, Andrew Emili, Dennis Joneswith CD8a-APC antibody (BioLegend, cat. #100712, RRID: AB_312751) and CD4-PE-Cy7 (BioLegend, cat. #100422, RRID: AB_312707). To analyze human CD8+ and CD4+ T-cell proliferation, CFSE-labeled cells were stained

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4/26/2021Detection of Mouse CD4s with PE/Cy7 Antibody Preeyam PatelWe are interested in detecting CD4 T cells in various mouse tissues.

PE/Cyanine7 anti-mouse CD4 from BioLegend

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PE/Cyanine7 anti-mouse CD4 from BioLegend

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