Supplier Page from Novus Biologicals, a Bio-Techne Brand for DC-SIGNR/CD299/CLEC4M Antibody (16E7) [Alexa Fluor® 700] - Chimeric
Available conjugates: Available conjugates: Alexa Fluor 700Specificity: Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.Sizes Available: 0.1 ml