Supplier Page from Novus Biologicals, a Bio-Techne Brand for Fc gamma RIIIA/CD16a Antibody (DJ130c) [DyLight 350]
Available conjugates: Available conjugates: CoraFluor 1, Alexa Fluor 350, DyLight 594, Janelia Fluor 525, DyLight 350, HRP, PE/Cy5.5, PE/Cy7, Allophycocyanin, Janelia Fluor 669, Alexa Fluor 594, PerCP, Janelia Fluor 549, DyLight 650, Alexa Fluor 750, Janelia Fluor 646Specificity: NB100-64346 recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. DJ130c recognizes all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the DJ130c antibody recognizes an epitope in the first membrane-distal domain of CD16 and recognizes both CD16A and CD16B.Sizes Available: 0.1 ml