Fc gamma RIIIA/CD16a Antibody (DJ130c) [DyLight 680] NB100-64346FR from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemFc gamma RIIIA/CD16a Antibody (DJ130c) [DyLight 680]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $519.00Supplier Page View Company Product Page
Catalog NumberNB100-64346FR
Quantity0.1 ml
ApplicationsFlow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
Conjugate/TagDyLight 680
Format50mM Sodium Borate
ReactivityHuman
TargetFc gamma RIIIA/CD16a
IsotypeIgG1
CloneDJ130c
HostMouse
ImmunogenCD34 antigen
ClonalityMonoclonal
Antibody TypePrimary Antibodies
StorageStore at 4C in the dark
NCBI Gene AliasesCD16, CD16-II, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, FcGRIIIA, IGFR3, IMD20
NCBI Full Gene NameFc gamma receptor IIIa
Research AreaCell Biology, Cellular Markers, Cytokine Research, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Stem Cells
PurityProtein A or G purified

Specifications/Features

Available conjugates: Available conjugates: DyLight 680

Specificity: NB100-64346 recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. DJ130c recognizes all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the DJ130c antibody recognizes an epitope in the first membrane-distal domain of CD16 and recognizes both CD16A and CD16B.

Sizes Available: 0.1 ml

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