Anti-Rb (phospho S249) antibody ab4788 from Abcam

Product Specs
ItemAnti-Rb (phospho S249) antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab4788
ClonalityPolyclonal
Quantity50 µL
IsotypeIgG
HostRabbit
ApplicationsWB
Conjugate/TagUnconjugated
FormatPurified from rabbit serum by sequential epitope-specific chromatography. The antibody has been negatively preadsorbed using a non-phosphopeptide corresponding to the site of phosphorylation to remove antibody that is reactive with non-phosphorylated Rb protein. The final product is generated by affinity chromatography using a Rb-derived peptide that is phosphorylated at serine 249 and threonine 252
ModificationsPhospho-S249
Gene NameRb1
ReactivityHuman
NCBI Gene AliasesOSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110
Antibody TypePrimary Antibody
Research AreaOncology
TargetRB1 phospho S249
NCBI Full Gene NameRB transcriptional corepressor 1

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Biomarkers for Prostate Cancer Aggressiveness in Puerto Rican Men: Analysis of Phospho-Rb S249, N-cadherin, β-catenin, and E-cadherin Expression in Prostate BiopsiesPonce Health Sciences University Scientific JournalJuly 14, 2025Sheila M. Valle Valle Cortés, Jaileene Pérez Pérez Morales, Mariely Nieves Nieves Plaza, Raymond Quiñones Quiñones Alvarado, Gilberto Ruiz Ruiz Deyá, Juan C. Santa Santa Rosario, Pedro Santiago Santiago Cardonaprimary and secondary antibodies. The antibodies used in this study were Phospho-Rb S249 (Abcam, Cat. No. ab4788) 1:100, purified mouse anti-N-cadherin (BD Biosciences, Cat. No.610920) 1:125; β-catenin (Cell Signaling,

(2) Integrating Proteomic Analysis and Machine Learning to Predict Prostate Cancer AggressivenessStats (Basel)September 1, 2024Sheila M. Valle Valle Cortés, Jaileene Pérez Pérez Morales, Mariely Nieves Nieves Plaza, Darielys Maldonado, Swizel M. Tevenal Tevenal Baez, Marc A. Negrón Negrón Blas, Cayetana Lazcano Lazcano Etchebarne, José Feliciano, Gilberto Ruiz Ruiz Deyá, Juan C. Santa Santa Rosario, et al.(Cell Signaling, Danvers, MA; Cat. No. 3195S) 1:400; and Phospho-Rb S249 (Abcam, Waltham, MA, USA; Cat. No. ab4788) 1:100. The secondary antibody used was the Super Sensitive Link Label IHC kit (BioGenex, Fremont, CA,

(3) Hyper-phosphorylation of Rb S249 together with CDK5R2/p39 overexpression are associated with impaired cell adhesion and epithelial-to-mesenchymal transition: Implications as a potential lung cancer grading and staging biomarkerPLOS ONENovember 19, 2018Jaileene Pérez-Morales et al.phospho-Rb (S249), rabbit polyclonal, 1:500 for immunoblot and 1:100 for immunohistochemistry (Cat. No. ab4788, Abcam, Cambridge, MA for immunoblots, and Cat. No. SAB 1305397–400 μL, Sigma-Aldrich, St. Louis, MO

(4) Macrophage inflammatory protein-3alpha influences growth of K562 leukemia cells in co-culture with anticancer drug-pretreated HS-5 stromal cellsToxicologyJuly 30, 2008Ying Chu Lee, Tzeon-Jye Chiou, Woan-Fang Tzeng, Sin Tak Chu

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Anti-Rb (phospho S249) antibody from Abcam

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Anti-Rb (phospho S249) antibody from Abcam

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