Thymidine Phosphorylase/ECGF1 (D69B12) Rabbit mAb 4307S from Cell Signaling Technology

Product Specs
ItemThymidine Phosphorylase/ECGF1 (D69B12) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number4307S
Quantity100 µl
ApplicationsW, IP
ReactivityH
Targetthymidine phosphorylase
HostRabbit
NCBI Gene AliasesECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF
ClonalityMonoclonal
NCBI Full Gene Namethymidine phosphorylase
Research AreaApoptosis
CloneD69B12
Molecular Weight50

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Oncogenic KRAS-driven type I interferon signalling primes pancreatic cancer for necroptosisNat CommunJune 15, 2026Sofya Tishina, Alina Dahlhaus, Marta Manik, Lejla Mulalic, Janine Murr, Michael Kotliar, Hassan Rakhsh-Khorshid, Myrto Kostopoulou, Florian Hocher, Jenny Stroh, et al.MABC604 1:1000), p-AKT (Ser473) (Cell Signaling, 4060 1:1000), p-ERK (Thr202/Tyr204) (Cell Signaling, 4307 1:1000), p-IKBα (Cell Signaling, 9246 1:1000), p-MK2 (Thr334) (Cell Signaling, 3007 1:1000), p-MLKL

(2) Atg5 deficiency in macrophages protects against kidney fibrosis via the CCR6-CCL20 axisCell Communication and SignalingApril 9, 2024Yufeng Zhu, Jiexing Tan, Yuanzhan Wang, Yuhong Gong, Xiaoyong Zhang, Ziguo Yuan, Xinyu Lu, Huifang Tang, Zhiming Zhang, Xiaotao Jiang, et al.4060; 1:1000), ERK1/2 (Cell Signaling Technology, 9102; 1:1000), p-ERK1/2 (Cell Signaling Technology, 4307; 1:1000), PI3K (Cell Signaling Technology, 4257; 1:1000), p-PI3K (Cell Signaling Technology, 4228; 1:1000),

(3) MEK Inhibition Sensitizes Pancreatic Cancer to STING Agonism by Tumor Cell-intrinsic Amplification of Type I IFN SignalingClin Cancer ResAugust 15, 2023Razmik Ghukasyan, Keke Liang, Kevin Chau, Luyi Li, Charlotte Chan, Evan R. Abt, Thuc Le, Joon Y. Park, Nanping Wu, Alykhan Premji, et al.,Cell Signaling Technology,37849 VINCULIN,Cell Signaling Technology,13901 TYMP,Cell Signaling Technology,4307 TOTAL STAT3,Cell Signaling Technology,9139 PHOSPHO STAT3 Y705,Cell Signaling Technology,9145 PHOSPHO

(4) MEK Inhibition Sensitizes Pancreatic Cancer to STING Agonism by Tumor Cell–intrinsic Amplification of Type I IFN SignalingClinical Cancer ResearchAugust 15, 2023Razmik Ghukasyan, Keke Liang, Kevin Chau, Luyi Li, Charlotte Chan, Evan R. Abt, Thuc Le, Joon Y. Park, Nanping Wu, Alykhan Premji, et al.,Cell Signaling Technology,37849 VINCULIN,Cell Signaling Technology,13901 TYMP,Cell Signaling Technology,4307 TOTAL STAT3,Cell Signaling Technology,9139 PHOSPHO STAT3 Y705,Cell Signaling Technology,9145 PHOSPHO

(5) Thymidine phosphorylase facilitates retinoic acid inducible gene-I induced endothelial dysfunctionCell Death & DiseaseApril 26, 2023Adrian Baris, Eugenia Fraile-Bethencourt, Jaiden Eubanks, Sokchea Khou, Sudarshan Anandaccording to the manufacturer’s instructions. Anti-RIG-I (#3743), Anti- ISG15 (#2743), Anti-TYMP (#4307), Anti-IRF8 (#98344) and Anti- GAPDH (#5174) were all purchased from Cell Signaling. Anti-IRF1 (PA5-64093)

(6) The Effects of the Levosimendan Metabolites OR-1855 and OR-1896 on Endothelial Pro-Inflammatory ResponsesBiomedicinesMarch 16, 2023Hannah Kipka, Rebecca Schaflinger, Roland Tomasi, Kristin Pogoda, Hanna Mannellphospho-p38 MAPK (Thr180/Tyr182) (D3F9) XP™ (#4511), rabbit VCAM-1 (#12367), rabbit phospho-ERK1/2 (#4307), rabbit phospho-JNK (#4668), rabbit phospho-cjun (#320T), rabbit β-Actin (13E5) (#4790) antibodies

(7) Immune-Enhancing Effects of Limosilactobacillus fermentum in BALB/c Mice Immunosuppressed by CyclophosphamideNutrientsFebruary 19, 2023Kim S, Lee HH, Kang CH, Kang H, Cho H.nitrocellulose membranes, which were then incubated with primary antibodies against Erk (#9102), pErk (#4307), GAPDH (#5174) and then with secondary anti-rabbit IgG (#7074) and anti-mouse IgG (#7076), all obtained

(8) Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cellsCell reportsJanuary 11, 2022Abt ER, Le TM, Dann AM, Capri JR, Poddar S, Lok V, Li L, Liang K, Creech AL, Rashid K, et al.,Cell Signaling Technology,Cat#9718; RRID:AB_2118009 "anti-TYMP, rabbit monoclonal",Cell Signaling Technology,Cat#4307; RRID:AB_10549070 "anti-NT5C3A, rabbit polyclonal",Sigma-Aldrich,Cat#HPA010630; RRID:AB_2668319 "anti-DHFR,

(9) Insulin-Like Growth Factor 1 Attenuates the Pro-Inflammatory Phenotype of Neutrophils in Myocardial InfarctionFrontiers in immunologyJanuary 1, 2022Nederlof R, Reidel S, Spychala A, Gödecke S, Heinen A, Lautwein T, Petzsch P, Köhrer K, Gödecke A.blocked in Odyssey blocking buffer (LI-COR Biosciences) and analyzed with antibodies against phospho-ERK (4307), AKT (2920), phospho-AKT Ser473 (9271), phospho-STAT1 (9167) from Cell Signaling Technology or phospho-STAT6

(10) Development of Carbazole Derivatives Compounds against Candida albicans: Candidates to Prevent Hyphal Formation via the Ras1-MAPK PathwayJournal of fungi (Basel, Switzerland)August 25, 2021Park YK, Shin J, Lee HY, Kim HD, Kim J.(9102S Cell Signaling Technology, Danvers, MA, USA), and 1:1500 dilution for phospho-Cek1/phosphor-Mkc1 (4307T Cell Signaling Technology, Danvers, MA, USA) were used. For the loading control, β-actin antibody (ab8224

(11) Targeting Thymidine Phosphorylase With Tipiracil Hydrochloride Attenuates Thrombosis Without Increasing Risk of Bleeding in MiceArteriosclerosis, thrombosis, and vascular biologyFebruary 1, 2021Belcher A, Zulfiker AHM, Li OQ, Yue H, Gupta AS, Li W.Institute, WI) as mentioned before.24 Antibodies to phosphorylated AKT (4060S), pan-AKT (2920S), TYMP (4307S), and GST (glutathione S-transferase; 2624S) were purchased from Cell Signaling Technology (Danvers,

(12) GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actionsThe Journal of clinical investigationMarch 2, 2020Gerhard DM, Pothula S, Liu RJ, Wu M, Li XY, Girgenti MJ, Taylor SR, Duman CH, Delpire E, Picciotto M, et al.0.05% Tween 20 (PBS-T) and then incubated with GluN2B antibody (Ab) (Cell Signaling Technology, catalog 4307, 1:1000; rabbit) or GluN2A Ab (BD biosciences, catalog 612286, 1:1000, mouse) overnight. Membranes were

(13) Regulation of neutrophil function by selective targeting of glycan epitopes expressed on the integrin CD11b/CD18The FASEB JournalFebruary 1, 2020Matthias Kelm, Sylvain Lehoux, Veronica Azcutia, Richard D. Cummings, Asma Nusrat, Charles A. Parkos, Jennifer C. BrazilCell Signaling Technologies (Total Syk #131985, p-Syk Tyr323 #2715S, Total Erk1/2 #4695S, p-Erk1/2 Thr202/Tyr204 #4307T, Total P38 MAPK #86905, p-P38 MAPK Thr180/Try182 #4511). Statistics Statistical differences were determined

(14) Regulation of neutrophil function by selective targeting of glycan epitopes expressed on the integrin CD11b/CD18FASEB J.December 23, 2019Matthias Kelm, Sylvain Lehoux, Veronica Azcutia, Richard D. Cummings, Asma Nusrat, Charles A. Parkos, Jennifer C BrazilCell Signaling Technologies (Total Syk #131985, p-Syk Tyr323 #2715S, Total Erk1/2 #4695S, p-Erk1/2 Thr202/Tyr204 #4307T, Total P38 MAPK #86905, p-P38 MAPK Thr180/Try182 #4511). Statistics Statistical differences were determined

(15) Curcumin attenuates hypoxia/reoxygenation‑induced myocardial injuryMolecular medicine reportsDecember 1, 2019Wei W, Peng J, Li J.anti‑CHOP (mouse; dilution 1:1,000; cat. no. 2895; CST), anti‑p‑ERK1/2 (mouse; dilution 1:1,000; cat. no. 4307; CST), anti‑ERK1/2 (mouse; dilution 1:1,000; cat. no. 4695; CST), anti‑p‑p38 (rabbit; dilution 1:1,000;

(16) Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cellsNature metabolismNovember 1, 2019Wang C, Haas MA, Yang F, Yeo S, Okamoto T, Chen S, Wen J, Sarma P, Plas DR, Guan JL.AB5320, PMID: 25902404, Millipore, MA), IHC, 1:100; anti-phosphorylated (Thr202/Tyr204) ERK1/2 (Cat: 4307, PMID: 22027685,Cell Signaling, MA), IHC, 1:100; anti-phosphorylated S6 kinase (Thr389) (Cat: 9234,

(17) Exploiting MCL1 Dependency with Combination MEK + MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in KRAS-Mutant Non–Small Cell Lung CancerCancer DiscoveryDecember 1, 2018Varuna Nangia et al.with enzyme treatment (1:1000) using standard protocols. Antibodies used were: phospho-ERK (1:100, #4307 Cell Signaling) and cleaved caspase-3 (1:300, #9661 Cell Signaling). Bond Polymer Refine Detection (Leica

(18) Exploiting MCL-1 dependency with combination MEK + MCL-1 inhibitors leads to induction of apoptosis and tumor regression in KRAS mutant non-small cell lung cancerCancer DiscovSeptember 25, 2018Varuna Nangia, Faria M. Siddiqui, Sean Caenepeel, Daria Timonina, Samantha J. Bilton, Nicole Phan, Maria Gomez-Caraballo, Hannah L. Archibald, Chendi Li, Cameron Fraser, et al.with enzyme treatment (1:1000) using standard protocols. Antibodies used were: phospho-ERK (1:100, #4307 Cell Signaling) and cleaved caspase-3 (1:300, #9661 Cell Signaling). Bond Polymer Refine Detection (Leica

(19) CB1R-Mediated Activation of Caspase-3 Causes Epigenetic and Neurobehavioral Abnormalities in Postnatal Ethanol-Exposed MiceFrontiers in Molecular NeuroscienceFebruary 20, 2018Shivakumar Subbanna, Nagaraja N. Nagre, Madhu Shivakumar, Vikram Joshi, Delphine Psychoyos, Abdullah Kutlar, Nagavedi S. Umapathy, Balapal S. Basavarajappa

(20) Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increaseMolecular metabolismJanuary 1, 2018Gao Y, Vidal-Itriago A, Milanova I, Korpel NL, Kalsbeek MJ, Tom RZ, Kalsbeek A, Hofmann SM, Yi CX.

Be the First to Write a Review!

Thymidine Phosphorylase/ECGF1 (D69B12) Rabbit mAb

Thymidine Phosphorylase/ECGF1 (D69B12) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (29)

Reviews

Thymidine Phosphorylase/ECGF1 (D69B12) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map