Phospho-Bad (Ser136) (D25H8) Rabbit mAb 4366S from Cell Signaling Technology

Product Specs
ItemPhospho-Bad (Ser136) (D25H8) Rabbit mAb
CompanyCell Signaling Technology
Price $401.00 Inquire
Catalog Number4366S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, Mk
TargetBad (Ser99) phosphate
ModificationsBad (Ser99) phosphate
HostRabbit
NCBI Gene AliasesBBC2, BCL2L8
ClonalityMonoclonal
NCBI Full Gene NameBCL2 associated agonist of cell death
Research AreaApoptosis
IsotypeIgG
CloneD25H8
Molecular Weight23

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) LOC100506691 Is an Oncogenic Long Noncoding RNA that Promotes Growth and Motility of Lung Cancer CellsCancer Genomics - ProteomicsSeptember 1, 2025YU-HSUAN CHEN, CHIH-YUN YANG, PEI-JUNG LIU, WAN-CHUNG HU, KUO-CHENG LU, CHING-FENG CHENG, KUO-WANG TSAICell Signaling Technology, Inc.), Bad (1:1,000; #9239, Cell Signaling Technology, Inc.), Phospho-Bad (1:1,000; #4366, Cell Signaling Technology, Inc.), and ACTB (1:2000, MAB1501, EMD Millipore). Statistical analysis.

(2) The non-cytotoxic small molecule NPB does not inhibit BAD phosphorylation and forms colloidal aggregatesCommun Med (Lond)May 10, 2025John Maringa Githaka, Tomás Gutiérrez, Zhuang Zhuang Han, Joseph O. Primeau, Heather Muranyi, Howard S. Young, Brian D. Sykes, Olivier Julien, Ing Swie Gopingrabbit-anti-BAD (Sigma-Aldrich cat# B0684), rabbit-anti-BAD-Ser99 (clone D25H8, Cell signaling cat# 4366), rabbit-anti-BAD-Ser75 (Cell signaling cat# 9291) and mouse-anti-Tubulin (clone B-5-1-2, Sigma-Aldrich

(3) Pentagalloyl Glucose (PGG) Exhibits Anti-Cancer Activity against Aggressive Prostate Cancer by Modulating the ROR1 Mediated AKT-GSK3β PathwayInternational journal of molecular sciencesJune 26, 2024Sivaganesh V, Ta TM, Peethambaran B.(Cell signaling, USA, #14334S); Bad (Cell signaling, USA, #9239S); p-Bad-ser136 (Cell signaling, USA, #4366S); Snail (Cell signaling, USA, #3895S); Twist1 (Cell signaling, USA, #69366S); MMP-9 (Cell signaling,

(4) Methyl vinyl ketone and its analogs covalently modify PI3K and alter physiological functions by inhibiting PI3K signalingThe Journal of biological chemistryMarch 1, 2024Morimoto A, Takasugi N, Pan Y, Kubota S, Dohmae N, Abiko Y, Uchida K, Kumagai Y, Uehara T.(4B8) (#3025), phospho-IR (Tyr1150/1151) (#3021), Bad (D24A9) (#9239), phospho-Bad (Ser136) (D25H8) (#4366), phospho-GSK3β (Ser9) (D85E12) (#5558), β-actin (13E5) (#5125), phospho-ATG16L1 (Ser278) (#84300),

(5) Overcoming brain-derived therapeutic resistance in HER2+ breast cancer brain metastasisbioRxivFebruary 28, 2024Danyyl Ippolitov, Yi-Han Lin, Jeremy Spence, Aleksandra Glogowska, Thatchawan Thanasupawat, Jason Beiko, Marc R. Del Bigio, Xin Xu, Amy Wang, Raul Calvo, et al.Z B,1:1000 in 5% BSA - 4C overnight,N/A,N/A Phospho-Bad (Ser136) (D25H8),Cell Signaling Technology,4366,AB_10547878,Rabbit,Monoclonal,H M R Mk,1:1000 in 5% BSA - 4C overnight,N/A,N/A Phospho-EGF Receptor

(6) Inhibition of PRL2 Upregulates PTEN and Attenuates Tumor Growth in Tp53-deficient Sarcoma and Lymphoma Mouse ModelsCancer Res CommunJanuary 2, 2024Nguele Meke F, Bai Y, Ruiz-Avila D, Carlock C, Ayub J, Miao J, Hu Y, Li Q, Zhang ZY.(Cell Signaling Technology, catalog no. 14220, RRID: AB_2798429), p-BAD pS136 (Cell Signaling Technology, catalog no. 4366, RRID: AB_10547878), PCNA (Cell Signaling Technology, catalog no. 2586, RRID:AB_2160343), FoxO1 (Cell Signaling Technology

(7) PRL2 inhibition elevates PTEN protein and ameliorates progression of acute myeloid leukemiaJCI InsightOctober 9, 2023Colin Carlock, Yunpeng Bai, Allison Paige-Hood, Qinglin Li, Frederick Nguele Meke, Zhong-Yin Zhang(Cell Signaling Technology, catalog 3521, RRID:AB_2143550), and BAD S136 (Cell Signaling Technology, catalog 4366, RRID:AB_10547878). Secondary antibodies used were: anti–rabbit IgG, HRP-linked (Cell Signaling Technology,

(8) Non-small cell lung cancers (NSCLCs) oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitorsSignal Transduction and Targeted TherapySeptember 25, 2023Bopei Cui, Lifang Song, Qian Wang, Kelei Li, Qian He, Xing Wu, Fan Gao, Mingchen Liu, Chaoqiang An, Qiushuang Gao, et al.Cell Signaling Technology), Bad (1: 1000, 9292, Cell Signaling Technology), p-Bad (Ser136, 1: 1000, 4366, Cell Signaling Technology), p-Bad (Ser112,1: 1000, 5284, Cell Signaling Technology), Bax (1: 1000,

(9) Cerebroprotective Effect of 17β-Estradiol Replacement Therapy in Ovariectomy-Induced Post-Menopausal Rats Subjected to Ischemic Stroke: Role of MAPK/ERK1/2 Pathway and PI3K-Independent Akt ActivationInternational Journal of Molecular SciencesSeptember 19, 2023María C. Burguete, Teresa Jover-Mengual, María Castelló-Ruiz, Mikahela A. López-Morales, José M. Centeno, Alicia Aliena-Valero, Enrique Alborch, Germán Torregrosa, Juan B. Salommonoclonal antibody, which detects endogenous levels of BAD only when phosphorylated at Ser136 (D25H8; #4366;1:500; Cell Signaling Technology); (5) anti-Bad rabbit polyclonal antibody (#9292; 1:500; Cell Signaling Technology

(10) Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinomaCell death discoveryApril 28, 2023Yang J, Li S, He J, Xu Q, Xie M, Yang C, Wang H, Zhang Y, Wan Q, Xiang M.(#sc-8044 Santa Cruz Technology, Texas, USA), p-BADS112 (#5284; Cell Signaling Technology), p-BADS136 (#4366; Cell Signaling Technology), cytochrome c (#sc-13156; Santa Cruz Technology), cleaved caspase-3 (#9664;

(11) Activating Transcription Factor 3 Diminishes Ischemic Cerebral Infarct and Behavioral Deficit by Downregulating Carboxyl-Terminal Modulator ProteinInternational journal of molecular sciencesJanuary 24, 2023Kao MH, Huang CY, Cheung WM, Yan YT, Chen JJ, Ho YS, Hsu CY, Lin TN.PARP1(#9544), Akt (or PKB)(#9272), p-Akt(Ser473)(#4058), p-Akt(Thr308)(#9275), CTMP(#4612), p-Bad(Ser136)(#4366), Bad(#9292) (Cell signaling Technology, Inc., Danvers, MA, USA; 1:1000). Protein bands were visualized

(12) A Biflavonoid-Rich Extract from Selaginella doederleinii Hieron. against Throat Carcinoma via Akt/Bad and IKKβ/NF-κB/COX-2 PathwaysPharmaceuticals (Basel)December 2, 2022Sisi Wang, Dingrong Wan, Wenqi Liu, Xinyi Kang, Xiuteng Zhou, Fatemeh Sefidkon, Mohaddesehossadat Mahmoud Zadeh Hosseini, Ting Zhang, Xin Pan, Xinzhou YangMA, USA), phosopho-Akt (Ser473) (CST, #4060, MA, USA), Bad (CST, #9268, MA, USA), phosopho-Bad (CST, #4366, MA, USA), COX-2 (CST, #4842, MA, USA), NF-κB p65 (CST, #8242, MA, USA), phosopho-NF-κB p65 (CST, #3033,

(13) Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cellsJCI insightNovember 8, 2022Thomas K, Zondler L, Ludwig N, Kardell M, Lüneburg C, Henke K, Mersmann S, Margraf A, Spieker T, Tekath T, et al.anti–phospho-14-3-3ζ Thr232, Invitrogen, PA5-38398, anti–Bad D24A9; CST, 9239; anti–phospho-Bad Ser136 D25H8, CST, 4366; anti–β-actin, CST, 4967; anti–caspase-3, CST 9662; anti–phospho-c-Jun [Ser73] 9164, anti-ASK1 [EP553Y],

(14) Antagonistic roles of Ras-MAPK and Akt signaling in Integrin-K+ channel Complexes-mediated cellular apoptosisThe FASEB JournalSeptember 29, 2022Elena Forzisi, Wei Yu, Parth Rajwade, Federico SestiMEK1/2 (cat. #9122), FAK (cat #3285), phospho-FAK (Tyr576/577 cat #3281), phospho-Bad (Ser136, cat. #4366), phospho-Bad (Ser112, cat. #5284), Akt (cat. #9272) and phospho-Akt (ser 473 cat. #9271) were purchased

(15) Targeting the Ezrin Adaptor Protein Sensitizes Metastatic Breast Cancer Cells to Chemotherapy and Reduces Neoadjuvant Therapy–induced MetastasisCancer Research CommunicationsJune 17, 2022Victoria Hoskin, Abdi Ghaffari, Brian J. Laight, Sandip SenGupta, Yolanda Madarnas, Christopher J.B. Nicol, Bruce E. Elliott, Sonal Varma, Peter A. Greer(Cell Signaling Technology, catalog no. 9272), phospho-Serine136 Bad (D25H8, Cell Signaling Technology, catalog no. 4366), total Bad (Cell Signaling Technology, catalog no. 9292), phospho-Serine536 p65 NFκB (Cell Signaling Technology

(16) P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemiaNature CancerJune 6, 2022Kevin H. Lin, Justine C. Rutter, Abigail Xie, Shane T. Killarney, Camille Vaganay, Chaima Benaksas, Frank Ling, Gaetano Sodaro, Paul-Arthur Meslin, Christopher F. Bassil, et al.1:3000 in 5% BSA), p-GSK3β S9 (D85E12) (CST #5558 diluted 1:1000 in 5% BSA), p-BAD S136 (D25H8) (CST #4366 diluted 1:1000 in 5% BSA), XPO1 (C-1) (sc # 74454 diluted 1:100 in 5% BSA), cleaved-PARP (D64E10) (CST

(17) AXL inhibition improves BRAF-targeted treatment in melanomaScientific reportsMarch 24, 2022Nyakas M, Fleten KG, Haugen MH, Engedal N, Sveen C, Farstad IN, Flørenes VA, Prasmickaite L, Mælandsmo GM, Seip K.(#4370) 1:2000, anti-ERK (#4695) 1:1000, anti-pS6 (#4858) 1:2000, anti-S6 (#2217) 1:1000, anti-pBAD (#4366) 1:1000, anti-BAD (#9292) 1:1000, anti-Mcl-1 (#4572) 1:1000, anti-LC3B (#2775) 1:1000. Anti-α-tubulin

(18) Preclinical evidence of a direct pro-survival role of arginine deprivation in multiple myelomaFrontiers in oncologyJanuary 1, 2022Trudu M, Oliva L, Orfanelli U, Romano A, Di Raimondo F, Sanvito F, Ponzoni M, Cenci S.anti-Akt (pan) (C67E7) (1:1000; Cell Signaling, 4691); rabbit anti-phospho BAD (1:1000; Cell Signaling, 4366); rabbit anti-BAD tot (1:1000; Cell Signaling, 9239); mouse anti-ACTB/b actin (1:5000; Sigma-Aldrich,

(19) BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathologyiScienceSeptember 24, 2021Zhang L, Qian Y, Li J, Zhou X, Xu H, Yan J, Xiang J, Yuan X, Sun B, Sisodia SS, et al.,Cell Signaling Technology,Cat# 4060; RRID:AB_2315049 Rabbit anti-p-BAD (S136),Cell Signaling Technology,Cat# 4366; RRID:AB_10547878 Rabbit anti-p-IKKα/β (Ser176/180),Cell Signaling Technology,Cat# 2697; RRID:AB_2079382 Rabbit

(20) Dietary fructose improves intestinal cell survival and nutrient absorptionNatureSeptember 1, 2021Taylor SR, Ramsamooj S, Liang RJ, Katti A, Pozovskiy R, Vasan N, Hwang SK, Nahiyaan N, Francoeur NJ, Schatoff EM, et al.1:1000, 1:500), LDHA (Rb, CST, 2012, 1:1000), MCL-1 (Rb, CST, 5453, 1:1000), pBad (S136) (Rb, CST, 4366, 1:1000), PDH (Rb, CST, 3205, 1:1000), pPDH (s293) (Rb, CST, 31866, 1:1000), PKLR (Rb, Abcam, 171744,

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Phospho-Bad (Ser136) (D25H8) Rabbit mAb

Phospho-Bad (Ser136) (D25H8) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-Bad (Ser136) (D25H8) Rabbit mAb from Cell Signaling Technology

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