GSK-3alpha/beta (D75D3) Rabbit mAb 5676S from Cell Signaling Technology

Product Specs
ItemGSK-3alpha/beta (D75D3) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number5676S
ClonalityMonoclonal
ApplicationsWB, IP
ReactivityHu, Ms, Rt, Hm, Mk
TargetGSK3-alpha;GSK3-beta
NCBI Full Gene Nameglycogen synthase kinase 3 beta, glycogen synthase kinase 3 alpha
Research AreaPI3K / Akt Signaling
IsotypeIgG
CloneD75D3
Molecular Weight51, 46
HostRabbit
Quantity100 µl

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) DP103 as a critical modulator of Wnt signaling and cancer stemness: implications for precision treatment in triple negative breast cancerCell Death & DiseaseJune 5, 2026Wanpei Cai, Sebastian Öther-Gee Pohl, Xianning Lai, Hiu Yan Lam, Catharine Shi-Yun Low, Vivien Koh, Haoran Ma, Mark Agostino, Arindam Banerjee, Nawat Bunnag, et al.(S33/S37/T41, #9561), anti-P-β-Catenin (S33/S37/T41) (D13A1, #8814), anti-PARP, anti-GSK3α/β (D75D3, #5676), anti-GSK3β (27C10, #9315S), anti-TCF4 (C48H11, #2569), anti-Dvl2 (Cell Signaling Technologies, #3216S)),

(2) Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathologyNat AgingMay 14, 2026Jun-Ping Pan, Ping-Jie Wang, Jianying Zhang, Anne-Brita Knapskog, Leiv Otto Watne, He-Ling Wang, Maria Jose Lagartos-Donate, Sofie Lautrup, Li-Peng Mao, Qian Wang, et al.catalog no. 3700); Rabbit monoclonal anti-GSK3 antibody (1:1,000, Cell Signaling Technology, catalog no. 5676); Rabbit monoclonal anti-Atg5 antibody (1:1,000, Cell Signaling Technology, catalog no. 12994); Rabbit

(3) FBXW7 Targets the SPT6-ΔNp63 Axis for Degradation to Inhibit Esophageal Tumorigenesis Induced by 4-Nitroquinoline N-OxideMedComm (2020)March 4, 2026Jiagui Zhang, Lu Yin, Xiahong You, Xiufang Xiong, Yi Sun17086‐1‐AP), EI24 (Proteintech, 20456‐1‐AP), NEDD8 (Abcam, ab81264), GSK3α/β (Cell Signaling Technology, 5676), c‐MYC (Cell Signaling Technology, 5605), p‐Ser/Thr‐Pro (05‐368, Upstate), FLAG (Sigma‐Aldrich, F1804),

(4) Non-enzymatic ABHD6 interacts with Akt-FoxO1 axis to regulate selective hepatic insulin resistancebioRxivFebruary 17, 2026Guannan Li, Laurence T. Maeyens, Jiyuan Yin, Jan-Bernd Funcke, Chanmin Joung, Ruizhen Li, Ziying Xu, Ting Wu, Xin Li, Nisi Jiang, et al.1:1000), Akt (pan) (CST, #4691, 1:1000), phospho-GSK3α/β (Ser21/9) (CST, #8566, 1:1000), GSK3α/β (CST, #5676, 1:1000), phospho-ACLY (Ser455) (CST, #4331, 1:1000), ACLY (CST, #4332, 1:1000), phospho-PRAS40 (Thr246)

(5) ZFTA–RELA ependymomas make itaconate to epigenetically drive fusion expressionNatureFebruary 4, 2026Siva Kumar Natarajan, Joanna Lum, James Haggerty Skeans, Minal Nenwani, Sanjana Eyunni, Mateus Mota, Jill M. Bayliss, Akash Deogharkar, Erin Taya Hamanishi, Matthew Pun, et al.1:1,000); pGSK3α/β (Cell Signaling Technology, 9331, 1:1,000); GSK3α/β (Cell Signaling Technology, 5676, 1:1,000); H3K4me3 (Cell Signaling Technology, 9751, 1:1,000); H3K9me3 (Cell Signaling Technology, 13969,

(6) Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liverMolecular OncologyFebruary 3, 2026Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. AltomarePhospho‐GSK‐3α/β (Ser21/9) (#9331) (Cell Signaling Technology or CST, Danvers, MA, USA), GSK‐3α/β (CST, #5676), β‐tubulin (CST, #2128), and β‐actin (SCBT, #sc‐8432) overnight at 4 °C. Blots were then incubated

(7) METTL16-m6A-PGC-1α axis contributes to exercise-induced mitochondrial adaptations in skeletal muscle of high-fat diet-fed insulin-resistant miceBMC BiologyJanuary 22, 2026Cong Chen, Cai Jiang, Qing Xiang, Yue Hu, Huijuan Wu, Chunxiu Huang, Huanghao Zhou, Ying Xu, Meijin Hou, Weilin Liu, et al.anti-MTCO1 (459,600, Invitrogen), anti-ATP5A1 (459,240, Invitrogen), anti-PGC1α (2178, CST), anti-GSK (5676, CST), anti-phospho-GSK-3α/β-S21/9 (9331, CST), anti-AKT (9272, CST), anti-phospho-AKT-Ser473 (4060,

(8) A Druggable Tumor Suppressor and Leukemic Stem Cell MarkerbioRxivJanuary 16, 2026Yi Pan, Xiaduo Meng, Chen Wang, Wenxuan Zhou, Yibo Chen, Richard D. Hammer, Hong Zheng, Gerhard Hildebrandt, Xunlei KangS2448 (ABclonal, Ap0115), p-mTOR S2481 (ABclonal, AP0978), GSK-3α/ß (Cell Signaling Technologies, #5676), p-GSK-3ß S9 (Cell Signaling Technologies, #9336), β-actin (Santa Cruz Biotechnologies, sc-47778). Flow cytometry

(9) Early branched-chain amino acid reduction delays the onset of cognitive decline in a mouse model of Alzheimer's diseaseJournal of Alzheimer’s DiseaseDecember 1, 2025Caitlyn A Mullins, Ritchel B Gannaban, Alyssa Kramer, Harsh Shah, Zobayda Farzana Haque, Marjan Ramezan, Fereshteh Dehghani, Arun Kumar Palaniyappan, Frances Bowers, Sheba MJ MohanKumar, et al.BSA and 0.1% sodium azide for pGSK-3α/β (Cell Signaling, Cat# 9331S), GSK-3α/β (Cell Signaling, Cat# 5676S), pTau Ser202 (Abcam, Cat# ab108387), Tau (Cell Signaling, Cat# 30328), IDE (Invitrogen, Waltham, MA,

(10) Bipolar and schizophrenia risk gene AKAP11 encodes an autophagy receptor coupling the regulation of PKA kinase network homeostasis to synaptic transmissionNature CommunicationsNovember 28, 2025You-Kyung Lee, Cong Xiao, Xiaoting Zhou, Le Wang, Meghan McReynolds, Zhiping Wu, Xian Han, Eric Purisic, Henry Kim, Xianting Li, et al.(Thermo, PA5-27581), Rabbit anti-Synaptophysin (Thermo, MA5-14532), Rabbit anti-GSK3α/β (Cell signaling, 5676S), Rabbit anti-p-GSK3α/β (S21/S9) (Cell signaling, 9331S), Rabbit anti-p-GluA1S845 (Cell signaling, 8084),

(11) The Differential Involvement of α1-Adrenoceptor Subtypes in the Molecular Effects of Antidepressant DrugsInternational Journal of Molecular SciencesOctober 28, 2025Irena Nalepa, Katarzyna Chorązka, Grzegorz Kreiner, Agnieszka Zelek-Molik, Anna Haduch, Władysława Anna Daniel, Piotr Chmielarz, Katarzyna Maziarz, Justyna Kuśmierczyk, Michał Wilczkowski, et al.p(S21/9)GSK3α/β (1:1000, cat. 9331, Cell Signaling Technology, Danvers, MA, USA); GSK3α/β (1:1000, cat. 5676, Cell Signaling Technology, Danvers, MA, USA). All Western blot analyses were performed at least twice

(12) Excitatory cortical neurons from CDKL5 deficiency disorder patient-derived organoids show early hyperexcitability not identified in neurogenin2 induced neuronsNeurobiology of DiseaseOctober 15, 2025Madison R. Glass, Dosh Whye, Nickesha C. Anderson, Delaney Wood, Nina R. Makhortova, Taryn Polanco, Kristina H. Kim, Kathleen E. Donovan, Gayathri Rajaram Srinivasan, Lorenzo Vaccaro, et al.(Cell Signaling Technologies #4691S), 1:500 p-GSK (Cell Signaling Technologies #5558), 1:500 GSK (Cell Signaling Technologies #5676S). 1:4000 Acetylated tubulin (Sigma #T7451), 1:4000 TUJ1 (Sigma #T8660), 1:4000 Tyrosinated tubulin (Millipore

(13) Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screeningNat CommunOctober 6, 2025Andreas Holmqvist, Nur Mehpare Kocaturk, Christina Duncan, Jennifer Riley, Steven Baginski, Graham Marsh, Joel Cresser-Brown, Hannah Maple, Kristiina Juvonen, Gajanan Sathe, et al.anti-c-Myc (Cell Signalling Technologies, 5605S, 1:1000), anti-GSK3 (Cell Signalling Technologies, 5676, lot 7, 1:1000), anti-β-actin (Sigma-Aldrich, A3853, 1:2000), anti-phospho (Thr 509/514) CRMP2 (MRC-PPU

(14) GSK-3α regulates miRNAs associated with transcriptional and metabolic processes in human cardiomyocytes under hypoxiaBiochemical JournalSeptember 17, 2025Firdos Ahmad, Hezlin Marzook, Musa Idris, Omama I. Dawuod, Megna Srinivas, Asima Karim, Mohamed A. Saleh, Rizwan Qaisartemperature. The membrane was incubated with primary antibodies against GSK-3α/β (Cell Signaling Technology #5676S) and Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (Fitzgerald #10 R-G109a) overnight at 4°C. The

(15) Genetic Deletion of RHAMM Alleviates Hepatic Oxidative Stress, Reversing Thyroid Stimulating Hormone Elevation in Male Obese MiceCellsSeptember 16, 2025Tianzhen Wang, Helin Sun, Ayman K. Banah, Xiong Weng, Sharadha Dayalan Naidu, Dot Kisielewski, Abel Ang, John D. Hayes, Albena T. Dinkova-Kostova, Li Kang(Cell Signaling (Danvers, MA, USA), #20733S, #62262, #0409, #9271, #9272, #4370, #4695, #8566, and #5676). GAPDH (Cell Signaling, #5174) or β-actin (Cell Signaling, #4970) served as loading controls. 2.4.

(16) GSK-3α regulates miRNAs associated with transcriptional and metabolic processes in human cardiomyocytes under hypoxiaBiochem JSeptember 9, 2025Firdos Ahmad, Hezlin Marzook, Musa Idris, Omama I. Dawuod, Megna Srinivas, Asima Karim, Mohamed A. Saleh, Rizwan Qaisartemperature. The membrane was incubated with primary antibodies against GSK-3α/β (Cell Signaling Technology #5676S) and Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (Fitzgerald #10 R-G109a) overnight at 4°C. The

(17) Spatiotemporal differential regulation of extrasynaptic GluN2B receptor subunits and PSA-NCAM in brain aging and Alzheimer’s diseaseFrontiers in NeuroscienceAugust 29, 2025Oghenetega E. Imiruaye, Isis G. Perez, Brian C. Carson, Christian Crouzet, Jerome Garcia, Derick Han, Subhrajit Bhattacharya(Cell Signaling Technology Cat# 9331, RRID: AB_329830)",monoclonal,rabbit GSK-3α/β,AB_10547140,GSK-3α/β (D75D3) Rabbit mAb #5676,"H, M, R, Hm, Mk","(Cell Signaling Technology Cat# 5676, RRID: AB_10547140)",polyclonal,rabbit Caspase-9,AB_2068620,Caspase-9 (C9) Mouse mAb

(18) Avenanthramide-C Mitigates High-Fat Diet-Accelerated Alzheimer’s Pathologies via NOD1-Driven Neuroinflammation in 5×FAD MiceNutrientsAugust 19, 2025Ming Wang, Baoyuan Jin, Jia Xu, Chuang Wangdilutions) specific for p-GSK3β (Ser9) (#5558, D85E12, Cell Signaling, Danvers, MA, USA), GSK-3β (#5676, D75D3, Cell Signaling), p-Akt (Ser473) (#4060, D9E, Cell Signaling), Akt (#9272, C67E7, Cell Signaling),

(19) Repurposing the Antibiotic D-Cycloserine for the Treatment of Hyperpigmentation: Therapeutic Potential and Mechanistic InsightsInt J Mol SciAugust 10, 2025Ye-Jin Lee, Chang-Gu HyunTX, USA). Antibodies targeting phospho- and total forms of β-catenin (9561S, 25362S), GSK-3β (9322S, 5676S), CREB (9198S, 4820S), ERK (9102S, 9101S), p38 (9211S, 9212S), JNK (9251S, 9252S), and AKT (9271S, 9272S)

(20) Novel roles for the GPI-anchor cleaving enzyme, GDE2, in hippocampal synaptic morphology and functioneNeuroJuly 9, 2025Daniel Daudelin, Damani Sama-Borbon, Nan Zhang, Shanthini SockanathanpAKT(T308) (Cell Signaling Technology, #9275, 1:500; RRID:AB_329828), GSK3α/β (Cell Signaling Technology, #5676, 1:10,000; RRID:AB_10547140), pGSK3α/β (Cell Signaling Technology, #9331, 1:1,000; RRID:AB_329830),

Be the First to Write a Review!

GSK-3alpha/beta (D75D3) Rabbit mAb

GSK-3alpha/beta (D75D3) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (255)

Reviews

GSK-3alpha/beta (D75D3) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map