CD25/IL-2R alpha Antibody (143-13) [DyLight 488] NBP2-47725G from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemCD25/IL-2R alpha Antibody (143-13) [DyLight 488]
CompanyNovus Biologicals, a Bio-Techne Brand
Price $549.00Supplier Page View Company Product Page
Catalog NumberNBP2-47725G
Quantity0.1 ml
ApplicationsFlow Cytometry,Immunofluorescence,CyTOF-ready,Immunocytochemistry/ Immunofluorescence
Conjugate/TagDyLight 488
Format50mM Sodium Borate
PurityProtein A or G purified
ReactivityHuman
TargetCD25/IL-2R alpha
IsotypeIgG1 Kappa
Clone143-13
HostMouse
Antibody TypePrimary Antibodies
ImmunogenStimulated human leukocytes
ClonalityMonoclonal
Research AreaAdaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
StorageStore at 4C in the dark
NCBI Full Gene Nameinterleukin 2 receptor subunit alpha
NCBI Gene AliasesCD25, IDDM10, IL2R, IMD41, TCGFR, p55

Specifications/Features

Available conjugates: Available conjugates: DyLight 488

Specificity: Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This monoclonal antibody recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.

Sizes Available: 0.1 ml

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