Anti-Involucrin antibody [SY5] ab68 from Abcam

Product Specs
ItemAnti-Involucrin antibody [SY5]
CompanyAbcam
Price $439.00Supplier Page View Company Product Page
Catalog Numberab68
Quantity100 µg
ApplicationsFlow Cyt, ICC/IF, IHC-P
Conjugate/TagUnconjugated
Concentration1 mg/ml
ReactivityHuman
TargetIVL
CloneSY5
HostMouse
IsotypeIgG1
Gene NameIVL
Antibody TypePrimary Antibody
ClonalityMonoclonal
Research AreaOncology
NCBI Full Gene Nameinvolucrin

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Subcytotoxic transepidermal delivery using low intensity cold atmospheric plasmaSci RepJanuary 16, 2025Ga Ram Ahn, Hyung-Joon Park, Yu Jin Kim, Min Gyo Song, Hye Sung Han, Woo Geon Lee, Hyuck Ki Hong, Kwang Ho Yoo, Joon Seok, Kyu Back Lee, et al.membranes were probed with anti-claudin1 (1:2500; ab24584; Abcam, Cambridge, UK), anti-Occludin (1:2500; ab68; Abcam), anti-E-cadherin (1:2500; ab85679; Abcam), and anti-β-actin (1:1000; sc-47778; Santa Cruz Biotechnology)

(2) Disrupting TSLP-TSLP receptor interactions via putative small molecule inhibitors yields a novel and efficient treatment option for atopic diseasesEMBO molecular medicineJuly 1, 2024Adhikary PP, Idowu T, Tan Z, Hoang C, Shanta S, Dumbani M, Mappalakayil L, Awasthi B, Bermudez M, Weiner J, et al.Cat# A28174) were obtained from Invitrogen. Filaggrin (Cat# ab814688), CK14 (Cat# ab7800), IVL (Cat# ab68) antibodies were obtained from Abcam. PE anti-human CD252 (OX-40L) antibody was purchased from Biolegend

(3) β-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signalingScientific reportsDecember 15, 2023Kim HS, Kim HJ, Hong YD, Son ED, Cho SY.difluoride membrane (Invitrogen). Proteins were probed with primary antibodies against involucrin (ab68), IκBa (ab32518), phospho-NF-κB (Ser536; ab86299), and NF-κB (ab32536) from Abcam (Cambridge, MA, USA);

(4) Engineering edgeless human skin with enhanced biomechanical propertiesScience advancesJanuary 27, 2023Pappalardo A, Alvarez Cespedes D, Fang S, Herschman AR, Jeon EY, Myers KM, Kysar JW, Abaci HE.antibodies: keratin 14 (BioLegend, #906004), involucrin (Abcam, #ab27495), human-specific involucrin (Abcam, #ab68), loricrin (Abcam, #ab198994), filaggrin (Abcam, #ab221155), desmoglein 1 (Progen, #651111), desmoglein 3

(5) Vaginal microbiome-host interactions modeled in a human vagina-on-a-chipMicrobiomeNovember 26, 2022Mahajan G, Doherty E, To T, Sutherland A, Grant J, Junaid A, Gulati A, LoGrande N, Izadifar Z, Timilsina SS, et al.ab40772 at 1:200 dilution), ZO-1 (Abcam, cat. no. ab276131 at 1:40 dilution), Involucrin (Abcam, cat. no. ab68 at 1:200 dilution), DSG1 (Abcam, cat. no. ab12077 at 1:400 dilution), and DSG3 (Abcam, cat. no. ab231309

(6) Keratin Promotes Differentiation of Keratinocytes Seeded on Collagen/Keratin HydrogelsBioengineering (Basel, Switzerland)October 15, 2022Zuniga K, Ghousifam N, Sansalone J, Senecal K, Van Dyke M, Rylander MN.5% FBS for 1 h and then incubated with anti-CK14 (ab181595, Abcam, Cambridge, UK), anti-involucrin (ab68, Abcam, Cambridge, UK), and anti-caspase 14 (ab174847, Abcam, Cambridge, UK) at 1:1000, 1:1000, and

(7) RAB3A Regulates Melanin Exocytosis and Transfer Induced by Keratinocyte-Conditioned MediumJID InnovationsSeptember 1, 2022LuÃs C. CabaÃ§o, Liliana Bento-Lopes, Matilde V. Neto, Andreia Ferreira, Wanja B.L. Staubli, JosÃ© S. Ramalho, Miguel C. Seabra, Duarte C. Barralsolution Anti‒keratin14,Mouse,Abcam (ab9220),Not applicable,"1:1,000 in Perblock solution" Anti-involucrin,Mouse,Abcam (ab68),Not applicable,1:200 in Perblock solution Anti-GAPDH,Goat,SICGEN (AB0049-500),"1:1,000 in blocking

(8) EGFR-mediated epidermal stem cell motility drives skin regeneration through COL17A1 proteolysisThe Journal of cell biologyNovember 1, 2021Nanba D, Toki F, Asakawa K, Matsumura H, Shiraishi K, Sayama K, Matsuzaki K, Toki H, Nishimura EK.antibody against loricrin (BioLegend; 905101, 1:100), mouse monoclonal antibody against IVL (Abcam; ab68, 1:500), rabbit monoclonal antibody against COL17A1 (Abcam; ab186415 and ab184996, 1:200), mouse monoclonal

(9) Microscopy-guided laser ablation for the creation of complex skin models with folliculoid appendagesBioengineering & translational medicineMay 1, 2021Abreu CM, Gasperini L, Lago MEL, Reis RL, Marques AP.Abcam), keratin (K) 10 (1:100; ab9026, Abcam), K14 (1:800; PRB‐155P, BioLegend), Involucrin (1:25, ab68, Abcam), fibronectin (1:100, ab2413, Abcam), K15 (1:50, ab80522, Abcam), β‐catenin (1:100, 610,154,

(10) Overall renewal of skin lipids with Vetiver extract for a complete anti‐ageing strategyInternational Journal of Cosmetic ScienceApril 1, 2021Morgane De Tollenaere, Emilie Chapuis, Laura Lapierre, Marine Bracq, Jane Hubert, Carole Lambert, Jérome Sandré, Daniel Auriol, Amandine Scandolera, Romain Reynaudanti‐dermokine beta rabbit antibody (ab26830; Abcam, Cambridge, UK) and anti‐involucrin rabbit antibody [Sy5] (ab68, Abcam). In vitro lipid accumulation on sebocytes Human SEBO662AR sebocyte cell lines were seeded

(11) Inhibition of tropomyosine receptor kinase B on the migration of human Schwann cell and dispersion of oral tongue squamous cell carcinoma in vitroHead & neckDecember 1, 2019Ein L, Bracho O, Mei C, Patel J, Boyle T, Monje P, Fernandez-Valle C, Bas E, Thomas G, Weed D, et al.against pan‐ cytokeratin (1:100, Novusbio, NBP2‐29429, Littleton CO), involucrin (1:100, Abcam, SY5, ab68, Cambridge, MA), S100 (1:100, Abcam, Ab868, Cambridge, MA), and Glial fibrillary acidic protein (GFAP;

(12) Glutaminolysis-related genes determine sensitivity to xCT-targeted therapy in head and neck squamous cell carcinomaCancer scienceNovember 1, 2019Okazaki S, Umene K, Yamasaki J, Suina K, Otsuki Y, Yoshikawa M, Minami Y, Masuko T, Kawaguchi S, Nakayama H, et al.antibodies (#12691, Cell Signaling Technology; 1:1000), involucrin with mouse monoclonal antibodies (ab68, Abcam; 1:200), ASCT2 with rabbit monoclonal antibodies (#8057, Cell Signaling Technology; 1:1000 dilution),

(13) LSD1 Inhibition Promotes Epithelial Differentiation through Derepression of Fate-Determining Transcription FactorsCell reportsAugust 20, 2019Egolf S, Aubert Y, Doepner M, Anderson A, Maldonado-Lopez A, Pacella G, Lee J, Ko EK, Zou J, Lan Y, et al.anti-Collagen VII,Millipore,Cat# 234192. RRID: AB_211739 Mouse monoclonal anti-Involucrin (SY5),Abcam,Cat# ab68. RRID: AB_305656 Rabbit polyclonal anti-Filaggrin,Abcam,Cat# ab81468. RRRID: AB_1640512 Rabbit polyclonal

(14) Filaggrin and tight junction proteins are crucial for IL-13-mediated esophageal barrier dysfunctionAmerican journal of physiology. Gastrointestinal and liver physiologySeptember 1, 2018Wu L, Oshima T, Li M, Tomita T, Fukui H, Watari J, Miwa H.(sc-66192) was purchased from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA). Mouse anti-involucrin (ab68) was purchased from Abcam (Cambridge, UK). Rabbit antiCLDN1, mouse anti-CLDN4, mouse anti-occludin,

(15) Topical administration of EGF suppresses immune response and protects skin barrier in DNCB-induced atopic dermatitis in NC/Nga miceScientific reportsAugust 9, 2018Kim YJ, Choi MJ, Bak DH, Lee BC, Ko EJ, Ahn GR, Ahn SW, Kim MJ, Na J, Kim BJ.membranes were probed with anti-filaggrin (1:2500; ab24584; Abcam, Cambridge, UK), anti-involucrin (1:2500; ab68; Abcam), anti-loricrin (1:2500; ab85679; Abcam), anti-occludin (1:1000; sc-5562; Santa Cruz Biotechnology,

(16) Decreased expression of cell adhesion genes in cancer stem-like cells isolated from primary oral squamous cell carcinomasTumour biology : the journal of the International Society for Oncodevelopmental Biology and MedicineMay 1, 2018Mishra A, Sriram H, Chandarana P, Tanavde V, Kumar RV, Gopinath A, Govindarajan R, Ramaswamy S, Sadasivam S.commercial antibodies were used for IHC: anti-CD44 (NCL-CD44-2; Leica Biosystems); anti-Involucrin (SY5, ab68; Abcam); anti-p63 (4A4, MU418-100; BioGenex); anti-CD45 (BioGenex) and Peroxidase AffiniPure Goat Anti-Mouse IgG (H + L

(17) Thymus transplantation for complete DiGeorge syndrome: European experienceThe Journal of Allergy and Clinical ImmunologyDecember 1, 2017E. Graham Davies, Melissa Cheung, Kimberly Gilmour, Jesmeen Maimaris, Joe Curry, Anna Furmanski, Neil Sebire, Neil Halliday, Konstantinos Mengrelis, Stuart Adams, Jolanta Bernatoniene, Ronald Bremner, Michael Browning, Blythe Devlin, Hans Christian Erichsen, H. Bobby Gaspar, Lizzie Hutchison, Winnie Ip, Marianne Ifversen, T. Ronan Leahy, Elizabeth McCarthy, Despina Moshous, Kim Neuling, Malgorzata Pac, Alina Papadopol, Kathryn L. Parsley, Luigi Poliani, Ida Ricciardelli, David M. Sansom, Tiia Voor, Austen Worth, Tessa Crompton, M. Louise Markert, Adrian J. Thrasher

(18) CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinomaPloS oneJanuary 1, 2017Dziunycz PJ, Neu J, Lefort K, Djerbi N, Freiberger SN, Iotzova-Weiss G, French LE, Dotto GP, Hofbauer GF.antibodies were used: actin (sc-1616), p21 (sc-6246), Notch1 (sc-6014) (Santa Cruz), involucrin (Abcam, ab68) loricrin, filaggrin, Hes1 (AB5702) and CYFIP1 (07–531) (Millipore). Immunohistochemistry was performed

(19) SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma PathogenesisPLoS biologyNovember 1, 2016Kim BR, Van de Laar E, Cabanero M, Tarumi S, Hasenoeder S, Wang D, Virtanen C, Suzuki T, Bandarchi B, Sakashita S, et al.(Molecular Devices). Primary antibodies for immunofluorescence staining were α-BTUB4 (#T7941, Sigma, 1:100), α-IVL (#ab68, Abcam, 1:1000), α-KRT5 (#ab24647, Abcam, 1:100), α-MUC5AC (Santa Cruz, #sc-20118, 1:100), α-MUC16 (#ab693,

(20) 3D map of the human corneal endothelial cellScientific reportsJuly 6, 2016He Z, Forest F, Gain P, Rageade D, Bernard A, Acquart S, Peoc'h M, Defoe DM, Thuret G.proteins,CD44,mouse,Abcam,Ab6124,M,+,no Negative controls,CK20,mouse,Dako,M7019,PFA,−, Negative controls,CK3/12,mouse,Abcam,ab68–260,PFA,−, Negative controls,CK5/6,mouse,Dako,M7237,PFA,−, Negative controls,α-SMA,mouse,Abcam,ab7817,PFA,−, Negative

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Anti-Involucrin antibody [SY5] from Abcam

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Anti-Involucrin antibody [SY5] from Abcam

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