Anti-Synaptophysin antibody GTX100865 from GeneTex

Product Specs
ItemAnti-Synaptophysin antibody
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX100865
ApplicationsWB, ICC/IF, IHC-P, IHC-Fr, IHC-Wm
ClonalityPolyclonal
Quantity25 µl
HostRabbit
Conjugate/TagUnconjugated
FormatPBS, 20% Glycerol, 0.025% ProClin 300
ReactivityHuman, Mouse, Rat
ImmunogenRecombinant protein encompassing a sequence within the C-terminus region of human Synaptophysin. The exact sequence is proprietary
Concentration1.65mg/ml
IsotypeIgG
Antibody TypePrimary Antibodies
NCBI Full Gene Namesynaptophysin
NCBI Gene AliasesXLID96, MRX96, synaptophysin, MRX96, MRXSYP, MRXSYP
PurityPurified by antigen-affinity chromatography
TargetSynaptophysin
Research AreaNeuroscience, Cell Markers
Gene NameSYP
Molecular Weight34

Questions and Answers

Can this antibody be used for Western blotting in my research on synaptic proteins?

Yes, the Anti-Synaptophysin antibody has been shown to be effective for Western blotting applications, as evidenced by its use in studies such as those by Chiu et al. (2023) and Donadon et al. (2019), where it was utilized to probe synaptophysin in various experimental setups.

Is this antibody suitable for immunohistochemistry in mouse models?

The Anti-Synaptophysin antibody has been validated for immunohistochemistry, including both paraffin-embedded and frozen sections. It has been cited in studies like Crncec et al. (2018) and Huang et al. (2024), where it was employed to analyze synaptic structures in mouse tissues.

What species does this antibody recognize, and is it effective for multiple models?

This antibody recognizes synaptophysin in human, mouse, and rat tissues, making it versatile for various experimental models in neuroscience research. Its reactivity across these species has been confirmed in multiple studies, including those referenced in the literature.

How does this antibody perform in immunofluorescence applications?

The Anti-Synaptophysin antibody has been successfully used in immunofluorescence applications, as demonstrated in studies such as those by Du et al. (2022) and Donadon et al. (2019), where it was utilized to visualize synaptic markers in neuronal cells and tissues.

GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) AAV-mediated intracerebral expression of an α-synuclein-targeting intrabody improves motor functions in aged ratsScientific ReportsJanuary 7, 2026Kuo-Jen Wu, Yu-Sung Chiu, Seong-Jin Yu, Yu-Syuan Wang, Chun-Tien Chen, Yu-Chen Peng, Yao-Ming Chuang, Chia-Ying Chu, Yin-Chia Li, Kun-Liang Wang, et al.rabbit polyclonal antibodies against PSD95 (1:2,500; #GTX133091, GeneTex) and synaptophysin (1:2,500; #GTX100865, GeneTex). Measurements of dopamine and cytokines The striatum homogenates were prepared as described

(2) Effect of New Antidiabetics on Steatosis in Nerve Tissues and Nerve Conduction Velocity: Possible Role of Nerve Growth Factor (NGF)/Synaptophysin and Nrf2/HO-1 PathwaysCureusJuly 1, 2024Abdel-Halim NHM, Eid EA, Yehya YM, Taha M, Mosa AAH, Ammar O, Nasr ANA, Hussin E, Hussein AM.GTX03258, GeneTex, Inc, CA, USA, dilution 1: 200) and synaptophysin NGF (polyclonal antibody, Cat # GTX100865, GeneTex, Inc, CA, USA, dilution 1: 500) at 4°C overnight after serum had blocked non-specific binding.

(3) FMOD Alleviates Depression-Like Behaviors by Targeting the PI3K/AKT/mTOR Signaling After Traumatic Brain InjuryNeuromolecular medicineJune 12, 2024Huang X, Zhu Z, Du M, Wu C, Fu J, Zhang J, Tan W, Wu B, Liu L, Liao ZB.BIO, 250,027, China), FMOD (GeneTex, GTX102783, USA), PSD95 (GeneTex, GTX22723, USA), SYP (GeneTex, GTX100865, USA), MAP2 (Proteintech, 17,490-1-ap, China), PI3K (Zenbio, 251,221, China), p-PI3K (Zenbio, 310,164,

(4) The lncRNA TPT1-AS1 promotes the survival of neuroendocrine prostate cancer cells by facilitating autophagyAmerican journal of cancer researchJanuary 1, 2024Chen PA, Chang PC, Yeh WW, Hu TY, Hong YC, Wang YC, Huang WJ, Lin TP.

(5) Defects in microvillus crosslinking sensitize to colitis and inflammatory bowel diseaseEMBO reportsOctober 9, 2023Mödl B, Awad M, Zwolanek D, Scharf I, Schwertner K, Milovanovic D, Moser D, Schmidt K, Pjevac P, Hausmann B, et al.and cleaved Caspase 3‐positive cells. The following antibodies were used: anti‐synaptophysin (GeneTex GTX100865), anti‐lysozyme (Dako A0099), anti‐BrdU (abcam, #ab6326), and anti‐cleaved Caspase 3 (CST, #9661L). Immunofluorescence Immunofluorescence

(6) REST-repressed lncRNA LINC01801 induces neuroendocrine differentiation in prostate cancer via transcriptional activation of autophagyAmerican journal of cancer researchJanuary 1, 2023Chang CH, Cheng TY, Yeh WW, Luo YL, Campbell M, Kuo TC, Shen TW, Hong YC, Tsai CH, Peng YC, et al.

(7) Peptide immunization against the C-terminal of alpha-synuclein reduces locomotor activity in mice overexpressing alpha-synucleinPloS oneJanuary 1, 2023Chiu YS, Wu KJ, Yu SJ, Wu KL, Wang YS, Lin J, Chu CY, Chen S, Chen H, Hsu SC, et al.GFAP (1:2,500; #GTX108711, GeneTex), PSD95 (1:2,500; #GTX133091, GeneTex), Synaptophysin (1:2,500; #GTX100865, GeneTex), and Ser-129 phospho-αSyn (1:1,000; #GTX50222, GeneTex), and one rabbit monoclonal antibody

(8) A novel circular RNA, circIgfbp2, links neural plasticity and anxiety through targeting mitochondrial dysfunction and oxidative stress-induced synapse dysfunction after traumatic brain injuryMolecular psychiatryNovember 1, 2022Du M, Wu C, Yu R, Cheng Y, Tang Z, Wu B, Fu J, Tan W, Zhou Q, Zhu Z, et al.antibodies were HO-1 antibody (ZEN BIO, 384541, China), PSD95 (GeneTex, GTX22723, USA), and Syn (GeneTex, GTX100865, USA). The fluorescence in situ hybridization (FISH) kit was obtained from RiboBio (China), and FISH

(9) CCL5 promotion of bioenergy metabolism is crucial for hippocampal synapse complex and memory formationMolecular psychiatryNovember 1, 2021Ajoy R, Lo YC, Ho MH, Chen YY, Wang Y, Chen YH, Jing-Yuan C, Changou CA, Hsiung YC, Chen HM, et al.

(10) Prognostic significance of the aberrant expression of neuroendocrine markers in melanomasDiagnostic pathologyAugust 28, 2021Wu Y, Lai Y, Zhang M, Li Z.

(11) Paradoxical changes in mood-related behaviors on continuous social isolation after weaningExperimental brain researchAugust 1, 2021Matsumoto H, Omata N, Kiyono Y, Mizuno T, Mita K, Kosaka H.

(12) Mice carrying an analogous heterozygous dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathyHuman molecular geneticsMay 28, 2020Pereira JA, Gerber J, Ghidinelli M, Gerber D, Tortola L, Ommer A, Bachofner S, Santarella F, Tinelli E, Lin S, et al.

(13) IDO1⁺ Paneth cells promote immune escape of colorectal cancerCommunications biologyMay 22, 2020Pflügler S, Svinka J, Scharf I, Crncec I, Filipits M, Charoentong P, Tschurtschenthaler M, Kenner L, Awad M, Stift J, et al.1 : 100), STAT1 (Santa Cruz, sc-592, 1 : 500), STAT3 (Santa Cruz, sc-7179, 1 : 80), Synaptophysin (GeneTex, GTX100865, 1 : 1000), GFP (Roche, 11814460001, 1 : 1000), red fluorescent protein (RFP) (Rockland antibodies and

(14) Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNANucleic acids researchAugust 22, 2019Donadon I, Bussani E, Riccardi F, Licastro D, Romano G, Pianigiani G, Pinotti M, Konstantinova P, Evers M, Lin S, et al.primary antibodies in blocking solution (Neurofilament, Sigma N4142, 1:8000 and Synptophysin, Genetex GTX100865, 1:200) with gentle shaking for 60 h in the cold room. Muscle bundles were washed with 5 ml of blocking

(15) Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4The American journal of pathologyAugust 1, 2019Bilousova T, Melnik M, Miyoshi E, Gonzalez BL, Poon WW, Vinters HV, Miller CA, Corrada MM, Kawas C, Hatami A, et al.

(16) Sustained pain hypersensitivity in the stressed colon: Role of mast cell-derived nerve growth factor-mediated enteric synaptic plasticityNeurogastroenterology and motility : the official journal of the European Gastrointestinal Motility SocietySeptember 1, 2018Zhang L, Song J, Bai T, Wang R, Hou X.

(17) STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancerMolecular oncologyApril 1, 2018Crnčec I, Modak M, Gordziel C, Svinka J, Scharf I, Moritsch S, Pathria P, Schlederer M, Kenner L, Timelthaler G, et al.#sc‐7179), phospho‐STAT3 (Tyr705) (Cell signaling #9145), lysozyme (Dako #A0099), synaptophysin (Genetex GTX100865), endomucin (eBioscience #14‐5851‐82), granzyme B (Abcam #ab4059), p21 (Santa Cruz #sc‐6246), c‐Myc

(18) EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of PatientsGastroenterologyJuly 1, 2017Srivatsa S, Paul MC, Cardone C, Holcmann M, Amberg N, Pathria P, Diamanti MA, Linder M, Timelthaler G, Dienes HP, et al.

(19) Enforcement of developmental lineage specificity by transcription factor Oct1eLifeMay 24, 2017Shen Z, Kang J, Shakya A, Tabaka M, Jarboe EA, Regev A, Tantin D.

(20) Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4RScientific reportsMay 2, 2017Pfanzagl B, Mechtcheriakova D, Meshcheryakova A, Aberle SW, Pfragner R, Jensen-Jarolim E.from Life Technologies, FITC-conjugated goat anti-IgG was from Millipore, rabbit anti-synaptophysin (GTX100865) was from GeneTex, goat anti-CgA and mouse anti-CD23[BU38] were from Santa Cruz, the 5-HT ELISA kit

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6/1/2021Reliable Synaptophysin Antibody ManHau HoThe antibody was used to detect synaptophysin expression in hippocampal total protein and synaptic protein by western bolt.

Anti-Synaptophysin antibody

Anti-Synaptophysin antibody

Anti-Synaptophysin antibody

Anti-Synaptophysin antibody

Anti-Synaptophysin antibody from GeneTex

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Anti-Synaptophysin antibody from GeneTex

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