MyBioSource.com's Goat Anti-Complement C3, C3c Antibody is a Goat Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA. The Goat Anti-Complement C3, C3c Antibody was generated using C3 as the antigen and it reacts with Human.
Description
C3c is the major fragment resulting from C3 cleavage by C3 convertase and factor I. It is composed of an intact beta chain bound to two fragments of the alpha chain. Locally deposited immune complexes in tissue usually contain complement, pointing to activation of the classical pathway. Complement activation in vivo implies active disease and may contribute to the elicitation of the pathogenesis and the extent of tissue destruction