MyBioSource.com's Rabbit Anti-Neurofibromin / NF1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot. The Rabbit Anti-Neurofibromin / NF1 Antibody was generated using neurofibromin 1, and NF1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
NF1 Antibody, VRNF Antibody, Neurofibromin 1 Antibody, NFNS Antibody, WSS Antibody, Neurofibromin Antibody Description: Neurofibromin / NF1 appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene