MyBioSource.com's Rabbit Anti-GIPR / GIP Receptor Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed. The Rabbit Anti-GIPR / GIP Receptor Antibody was generated using GIPR as the antigen and it reacts with Human, Rat, Bovine, Canine, Hamster, Horse, Non-Human Primate, Rabbit, and Sheep.
Description
GIPR, or Gastric Inhibitory Polypeptide Receptor, mediates GIP-induced secretion of insulin by pancreatic islet beta cells after a meal. GIP is a gastrointestinal peptide hormone of 42 aa that is released from duodenal endocrine K cells after absorption of glucose or fat. Stimulation of the GIPR on pancreatic cells activates adenylyl cyclase and mitogen-activated protein kinase, resulting in increased insulin secretion