MyBioSource.com's RAD51 Antibody is a Mouse monoclonal antibody. The RAD51 Antibody was generated using RAD51 recombinase (RAD51) as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot.
Description
Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3