The Rabbit Anti-FSD2 / Frizzled 2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to FZD2. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, Hamster, Horse, Porcine, and Sheep antigen. The Rabbit Anti-FSD2 / Frizzled 2 Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
FZD2 is a Frizzled Receptor that mediates Wnt signaling, which is required for proper axis development in the embryo. FZD2 is developmentally regulated. Studies of rat FZD2 indicate that the protein signals through a calcium-releasing pathway and that FDZ2 expression modulates protein kinase C (PKC) localization and stimulates PKC activity in vitro. Increased levels of FZD2 mRNA have been observed in primary gastric cancer and in head and neck squamous carcinoma and gastric cancer cell lines