MyBioSource.com's b2-Microglobulin (B2M) Antibody is a Mouse monoclonal antibody. The b2-Microglobulin (B2M) Antibody was generated using HLA-G as the antigen. It reacts with Chicken/Bird. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Like their mammalian counterparts, avian MHC Class I molecules (also known as B-F antigens) consist of a highly polymorphic alpha-chain (Mr ~44kD) non-covalently bound to the invariant beta2-microglobulin subunit (Mr ~14kD). MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells.1-2