MyBioSource.com's Anti-Human CD155 (PVR) monoclonal antibody. The Anti-Human CD155 (PVR) Antibody was generated using PVR as the antigen. It reacts with Mouse. This antibody has been shown to work in applications such as: ELISA, and Flow Cytometry.
Description
Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70 kd type I Ig superfamily molecule (1).1 It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226(DNAM-1), and CD96(TACTILE). CD155 expression by tumor has been shown to be upregulated by Nitric Oxide(2). A soluble version of CD155 has been shown to exist (4). High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma. (3)