The Polymyxin B (PMB) Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The Polymyxin B (PMB) Antibody has been shown to work in the following applications: EIA, Immunoassay, Block/Neutralize/Inhibit, ELISA, and Western Blot.
Description
The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either in vitro or in vivo. The monoclonal antibody enables the possibility to study quantitatively the interaction of PMB and LPS