The Anti-Human CD155 (PVR) Antibody from MyBioSource.com Monoclonal antibody to PVR. This antibody recognizes Mouse antigen. The Anti-Human CD155 (PVR) Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Flow Cytometry.
Description
Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70 kd type I Ig superfamily molecule (1).1 It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226(DNAM-1), and CD96(TACTILE). CD155 expression by tumor has been shown to be upregulated by Nitric Oxide(2). A soluble version of CD155 has been shown to exist (4). High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma. (3)