MyBioSource.com's Rabbit Anti-Stromal Cell Derived Factor 1alpha Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, Block/Neutralize/Inhibit, ELISA, and Western Blot. The Rabbit Anti-Stromal Cell Derived Factor 1alpha Antibody was generated using CXCL12 as the antigen and it reacts with Human.
Description
Chemokine SDF-1 is highly conserved among species and belongs to a large family of small, structurally related cytokines. It is a chemoattractant for T lymphocytes, monocytes, and hemopoietic stem cells and is constitutively expressed in bone marrow-derived stromal cells. Recent reports indicate that SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. SDF-1a and SDF-1b, are generated by alternative RNA splicing of transcripts encoded by a single gene. SDF-1a differs from SDF-1b by four C-terminal amino acid residues absent in SDF-1a. As yet, no functional differences have been reported. Stromal Cell-Derived Factor-1 (SDF1) is a recently discovered protein belonging to the -chemokine (C-X-C) family of cytokines. Human SDF1 is an 8kD protein containing 68 amino acid residues