The Rabbit Anti-SMO / Smoothened Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SMO. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Hamster, Horse, Non-Human Primate, Porcine, Rabbit, Xenopus/Amphibian, and Other Mammalian antigen. The Rabbit Anti-SMO / Smoothened Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Smoothened, a Frizzled Receptor, is homologous to the Drosophila segment polarity Smo gene. It associates with the Patched protein to mediate the cellular response to the Hedgehog secreted protein signal, which controls patterning and growth during vertebrate development. Smoothened is activated in a number of human tumors and can function as an oncogene in basal-cell carcinomas