The Rabbit Anti-RORA / ROR Alpha Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to RORA. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, Horse, Non-Human Primate, Porcine, Rabbit, Xenopus/Amphibian, Zebrafish/Fish, and Other Mammalian antigen. The Rabbit Anti-RORA / ROR Alpha Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Retinoid-related orphan receptor alpha (ROR alpha), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect the development of the central nervous system. Deletion of ROR alpha in mice causes severe impairment in the differentiation of cerebellar Purkinje neurons and results in the 'staggerer' phenotype. ROR alpha has been suggested as a potential target in the treatment of chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis