MyBioSource.com's Rabbit Anti-FZD5 / Frizzled 5 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed. The Rabbit Anti-FZD5 / Frizzled 5 Antibody was generated using FZD5 as the antigen and it reacts with Human, Mouse, Rat, Bovine, Canine, Non-Human Primate, Porcine, and Rabbit.
Description
FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway