MyBioSource.com's Fibroblast Growth Factor 2, Basic (FGF2b) Antibody is a Mouse monoclonal antibody. The Fibroblast Growth Factor 2, Basic (FGF2b) Antibody was generated using FGF2 as the antigen. It reacts with Human, Mouse, Rat, and Bovine. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot.
Description
FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF