Rabbit Anti-C3AR / C3a Receptor Antibody MBS247882 from MyBioSource.com

Description

The C3a Anaphylatoxin Receptor mediates the effects of the inflammatory mediator anaphylatoxin C3a, which is released during complement activation. This receptor stimulates chemotaxis, granule enzyme release, and superoxide anion production. It also regulates glial cell activation, may be involved in the pathogenesis of asthma, and may promote cell repair

Product Specs
ItemRabbit Anti-C3AR / C3a Receptor Antibody
CompanyMyBioSource.com
Price $495.00Supplier Page View Company Product Page
Catalog NumberMBS247882
Quantity0.05 mg
ApplicationsImmunohistochemistry (IHC - Paraffin)
Concentration1 mg/ml
Conjugate/TagUnconjugated
FormatPBS, 0.1% sodium azide
PurityImmunoaffinity Purified
ReactivityHuman
Predicted Reactivity: Gorilla, Orangutan, Gibbon, Monkey (at least 90% immunogen sequence identity)
TargetC3AR / C3a Receptor
Molecular Weight53,864 Da
HostRabbit
ImmunogenHuman C3a Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ADRA1A (40%)
NCBI Full Gene Namecomplement component 3a receptor 1
NCBI Gene AliasesC3AR, AZ3B, HNFAG09
ClonalityPolyclonal

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Questions and Answers

Can this antibody be used for studying the role of the C3a receptor in inflammation?

Yes, the Rabbit Anti-C3AR / C3a Receptor Antibody is designed to target the C3a Anaphylatoxin Receptor, which mediates the effects of the inflammatory mediator C3a. This receptor is known to stimulate chemotaxis, granule enzyme release, and superoxide anion production, making it relevant for research into inflammatory processes.

What species can I use this antibody with in my experiments?

This antibody is reactive with human and non-human primate samples, as well as macaque and other non-human primate species. This broad reactivity allows for its application in various biological studies involving these species.

Is this antibody suitable for immunohistochemistry applications?

Yes, the Rabbit Anti-C3AR / C3a Receptor Antibody has been specified for use in immunohistochemistry on paraffin-embedded tissues. This makes it a suitable choice for visualizing the expression of the C3a receptor in tissue samples.

What is the immunogen used for this antibody, and how specific is it?

The immunogen for this antibody is derived from the human C3a Receptor. BLAST analysis indicates that the peptide immunogen shows no significant homology with other human proteins, except for a 40% similarity with ADRA1A, suggesting a high level of specificity for the C3a receptor in experimental applications.