The NUMB Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NUMB. This antibody recognizes Human, Mouse, and Rat antigen. The NUMB Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene