ISG15 (F-9) Antibody sc-166755 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemISG15 (F-9) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-166755
Antibody TypePrimary Antibodies
NCBI Gene AliasesG1p2, Irfp, UCRP, IGI15, hUCRP, IFI15, IP17, G1P2, IMD38
Quantity200 µg/ml
CloneF-9
Reactivitymouse, rat, human
Conjugate/TagUnconjugated
FormatPurified
ApplicationsWB, IP, IF, IHC(P), ELISA
ClonalityMonoclonal
Hostmouse
NCBI Full Gene NameISG15 ubiquitin-like modifier, ISG15 ubiquitin like modifier
TargetISG15
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Dual Roles of hABCB1 in Drug Resistance and Immune Evasion: Implications for Lung Cancer TherapyACS OmegaMay 26, 2026Jin Young Min, Hye Min Kim, Geul Bang, Hae Won Jung, Yea Jin Kim, Sang-Yeop Lee, Dong Joon Kim, Sang Keun Ha, Truc Ngoc Kim Lam, Kwan Soo Hong, et al.Cell Signaling Technology; 1:1000), phospho-AKT (Ser473) (S9E, #4060, Cell Signaling Technology; 1:1000), ISG15 (sc-166755, Santa Cruz Biotechnology; 1:500), CXCL10 (sc-101500, Santa Cruz Biotechnology; 1:500), and β-actin

(2) Human ISG15 deficiency unveils impaired healing of ulcerations via type I interferon–mediated fibrosisJournal of Human ImmunityMay 4, 2026Christos Sazeides, Lorenzo Cuollo, Ikjot Sidhu, Haley E. Randolph, Marta Martin-Fernandez, Sofija Buta, O’ Jay Stewart, Rachel Geltman, Jonas A. Adalsteinsson, Robert G. Phelps, et al.each wash), and visualized on film. The primary antibodies used were the following: anti-ISG15 (F-9) (sc-166755; Santa Cruz), anti-LC3B (#2775; Cell Signaling), anti-GAPDH (D16H11) (#5174; Cell Signaling). Fig. 1

(3) Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus ErythematosusAdvanced ScienceMay 1, 2026Lele Zhang, Ming‐Ju Amy Lyu, Ze Hong, Jing Sun, Lan Guo, Jiameng Hu, Munire Maimaiti, Chenhui Li, Jinyi Song, Xiang Zhang, et al.(SC‐347092, Santa Cruz Biotechnology), rabbit anti‐ZBP1 (PRS4401, Sigma‐Aldrich), mouse anti‐ISG15 (SC‐166755, Santa Cruz Biotechnology), and rabbit anti‐IFIT3 (15201‐1‐AP, Proteintech). 5.13 Flow Cytometry Analysis Single‐cell

(4) Retinoic Acid-inducible Gene-I Increases Interferon-stimulated Gene 15 Expression in Human Renal Proximal Tubule Epithelial CellsIn VivoApril 28, 2026Mayuki Tachizaki, Shogo Kawaguchi, Hiroshi Tanaka, Tadaatsu Imaizumiantibodies used are as follows: Rabbit anti-RIG-I [1:10,000; described in (21)]; mouse anti-ISG15 (1:1,000; sc-166755; Santa Cruz Biotechnology, Santa Cruz, CA, USA); rabbit anti-UBA7 (1:1,000; TA307362; OriGene, Rockville,

(5) Innate immune sensing of dietary alcohol ignites inflammation to drive alcohol-related diseaseSci AdvApril 10, 2026Yeonseo Jang, Hoeun Bae, SuHyeon Oh, Gyeongju Yu, Hyun Bae, Minh Quan Nguyen, Raghvendra Mall, Minjie Fu, Aritra Ghosh, Jihye Lee, et al.phospho-p38 MAPK (1:1000; CST, 4511L), ADAR1 (1:250; Santa Cruz, sc-73408), ISG15 (1:250; Santa Cruz, sc-166755), β-actin (1:1000; CST, 8457S), and glyceraldehyde phosphate dehydrogenase (GAPDH; 1:50,000; Proteintech,

(6) Discovery of synthetic G-quadruplex DNA as SARS-CoV-2 helicase inhibitor with antiviral, anti-inflammatory and antioxidative propertiesCell Death DiscoveryMarch 18, 2026Denisa Bojkova, Katja Steinhorst, Marco Bechtel, Nadja Zoeller, Monika Doll, Melanie Ott, Florian Rothweiler, Tamara Rothenburger, Kristoffer Riecken, Boris Fehse, et al.Germany). HBE ALI lysates were analyzed with primary antibodies against GAPDH (#2118, 1:4000, CST), ISG15 (#sc-166755,1:200, Santa Cruz Biotechnology), Mx1 (#37849, 1:1000, CST), SARS-CoV-2 Nucleocapsid (#40143-R019, 1:10 000

(7) TRPM2 couples cell-autonomous type-I interferon signaling to pigmentation homeostasisbioRxivMarch 13, 2026Nutan Sharma, Abhishek Tanwar, Changyu Zheng, Indu Ambudkar, Rajender K MotianiAntibody,Company,Catalog Number,Species TRPM2,Abcam,ab11168,Mouse ISG15,Santa Cruz,sc-166755,Mouse Ubiquitin,Santa Cruz,sc-271289,Mouse MITF,Santa Cruz,sc-56725,Mouse DCT,Abcam,ab74073,Mouse TYR,Abcam,ab170905,Mouse GP100,Abcam,ab137078,Mouse Tubulin,Abcam,ab21058,Mouse Actin,Sigma-Aldrich,A3854,Mouse TBK-1,CST,38066,Mouse p-TBK-1,CST,5483,Mouse IRF-7,CST,72073,Mouse p-IRF-7,CST,24129,Mouse IRF-3,CST,4302,Mouse p-IRF-3,CST,29047,Mouse cGAS,CST,79978,Mouse STING,CST,13647,Mouse p-STING,CST,72971,Mouse

(8) A type I interferon-mitochondrial axis regulates efferocytosis and interferon-stimulated gene induction in macrophagesImmunityFebruary 10, 2026Gillian Dunphy, Irene Adán-Barrientos, Irene Fernández-Delgado, Carolina Villarroya-Beltri, Ignacio Heras-Murillo, Elena Moya-Ruiz, Miguel Sánchez-Álvarez, Aitor Jarit-Cabanillas, Miguel A. del Pozo, Susana Guerra, et al.(RUO),BD Biosciences,Cat#551461; RRID: AB_394208 Anti-ISG15 (Clone F-9),Santa Cruz Biotechnology,Cat#sc-166755; RRID: AB_2126308 "Mouse Anti-Mitochondrial ATP Synthase Subunit Beta Monoclonal Antibody, Unconjugated,

(9) Pseudorabies virus TK protein antagonizes alpha interferon response by interfering with the JAK1-STAT1 interactionVirologica SinicaJanuary 29, 2026Jingjing Song, Rulan Bai, Dongyue Xing, Chuang Li, Xuan Chen, Feiyang Zheng, Mingyi Lei, Yujin Wang, Yuxin Liu, Jun Tang, et al.p-STAT2 (88410) and HA (C29F4) from Cell Signaling Technology; Flag (F1804, Sigma-Aldrish), ISG15 (sc-166755, Santa Cruz Biotechnology) and tubulin (PM054, MBL). The polyclonal antibodies against viral proteins

(10) HIV-1 infection regulates gene expression by altering alternative polyadenylation correlated with CPSF6 and CPSF5 redistributionmBioJanuary 14, 2026Charlotte Luchsinger, Annie Zhi Dai, Hari Yalamanchili, Aiswarya Balakrishnan, Kai-Lieh Huang, Cinzia Bertelli, Bin Cui, Ramon Lorenzo-Redondo, Eric J. Wagner, Felipe Diaz-GrifferoCat# sc-393880, Santa Cruz), CPSF6 (clone F-3; Cat# sc-376228, Santa Cruz), ISG15 (clone F-9; Cat# sc-166755, Santa Cruz), and HIV-1 p24 (clone 183-H12-5C; Cat# ARP-3537, NIH AIDS Reagent Program). We used rabbit

(11) METTL3 abrogation promotes glioma progression through regulating the ISG15-FASN axis-mediated lipid metabolism in macrophagesNature CommunicationsJanuary 8, 2026Huilong Yin, Xiaoyi Yu, Chenglong Hu, Yuhang Yang, Mengke Wang, Yating Xing, Baile Zuo, Chenxing Zhang, Weilong Yang, Yitong Li, et al.Cell Signaling Technology), rabbit anti-AceCS1 (1:1000, 3658S, Cell Signaling Technology), Mouse anti-ISG15 (1:1000, sc-166755, Santa Cruz Biotechnology), mouse anti-FLAG (1:2000, Sigma), rabbit anti-FLAG (1:1000, 20543-1-AP, Proteintech),

(12) PCBP1 binding to single-stranded poly-cytosine motifs enhances cGAS sensing and impairs breast cancer developmentCommunications BiologyJanuary 7, 2026Cécile Fréreux, Joseph A. Q. Karam, Breege V. Howley, Bryan Granger, Paramita Chakraborty, Silvia Vaena, Martin Romeo, Annamarie C. Dalton, Bidyut K. Mohanty, Shikhar Mehrotra, et al.IRF7,Cell Signaling Technology,cat. no. 72073S Anti-mouse/human ISG15,Santa Cruz Biotechnology,cat. no. sc-166755 Anti-mouse/human PCBP1,MBL Life Science,cat. no. RN024P Anti-mouse phospho-IRF3,Cell Signaling Technology,cat.

(13) A New Model of Gastric Pre-neoplasia Induced by Aberrant ADAR1-mediated Double-stranded RNA SignalingCellular and Molecular Gastroenterology and HepatologyJanuary 1, 2026Angela M. Halstead, Chinye Nwokolo, Stella Hoft, Jinsheng Yu, Lifei Zhu, Brendan Tuley, Nancy Vargas, RuiRui Liu, Francisco Ramirez Victorino, Simrin Phatak, et al.,Cell Signaling Technologies,9172 "Anti-Phospho-STAT1 (Y701), rabbit",Cell Signaling Technologies,9167 "Anti-ISG15, mouse",Santa Cruz,sc-166755 "Anti-β-Actin, mouse",Sigma,A5441 "Cleaved-CASPASE 3, rabbit",Cell Signaling Technologies,9664 Anti-rabbit-HRP,Cell Signaling Technologies

(14) Nef stabilizes actin to prevent HIV-1 sensing by RIG-I-like receptorsNat CommunDecember 7, 2025Alexandre Laliberté, Caterina Prelli Bozzo, Dhiraj Acharya, Aurora De Luna, Maximilian Hirschenberger, Junji Zhu, Meta Volcic, Bettina Stolp, Cristina M. Rodriguez-Quinteros, Oliver T. Fackler, et al.Proteins were stained with primary antibodies mouse anti-ISG5 (1:500, Santa Cruz Biotechnology, Cat#sc-166755), rabbit anti-PAK2 (1:1000 Cell Signaling Technology, Cat#2608), rabbit anti-MAVS (1:1000, Cell Signaling

(15) MUCIN 1 confers inflammatory memory of tyrosine kinase inhibitor resistance in non-small cell lung cancerSignal Transduction and Targeted TherapyNovember 28, 2025Shinkichi Takamori, Naoki Haratake, Atrayee Bhattacharya, Chie Kikutake, Hiroki Ozawa, Keisuke Shigeta, Ayako Nakashoji, Hideko Isozaki, Mototsugu Shimokawa, Mikita Suyama, et al.CST), anti-OAS1 (#14498, 1:1000 dilution; CST), anti-MX1 (37849, 1:1000 dilution; CST), anti-ISG15 (sc-166755, 1:250 dilution; Santa Cruz, Santa Cruz Biotechnology), anti-PBRM1 (A301–591 A, 1:10000 dilution; Bethyl

(16) NAT10 Suppresses RNA Sensing Induced IFN-β Transactivation to Promote Viral Infection via Interfering with IRF3 ActivitiesbioRxivSeptember 11, 2025Youngmin Park, Jinshan He, Eleya Eleya, Zhenyu Zhenyu, Guillaume N Fiches, Dawei Zhou, Emily G Watters, Zhixian M He, Kateepe ASN Shanaka, Thurbu T Lepcha, et al.Santa Cruz Santa Cruz Biotechnology), anti-ISG15 Biotechnology), anti-IFIT3 (Cat # sc-393512, (Cat # sc-166755, Santa Cruz Biotechnology), anti-MX1 (Cat # sc-271399, Santa Cruz Biotechnology), anti-IFITM1 (Cat #

(17) HIV-1 Infection Regulates Gene Expression by Altering Alternative Polyadenylation Through CPSF6 and CPSF5 DelocalizationbioRxivAugust 7, 2025Charlotte Luchsinger, Annie Zhi Dai, Hari Yalamanchili, Aiswarya Balakrishnan, Kai-Lieh Huang, Cinzia Bertelli, Bin Cui, Ramon Lorenzo-Redondo, Eric J. Wagner, Felipe Diaz-GrifferoCat# sc-393880, Santa Cruz), CPSF6 (clone F-3; Cat# sc-376228, Santa Cruz), ISG15 (clone F-9; Cat# sc-166755, Santa Cruz), and HIV-1 p24 (clone 183-H12–5C; Cat# ARP-3537, NIH AIDS Reagent Program). We used rabbit

(18) Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch SignalsAdvanced ScienceJuly 18, 2025Xiaotong Zhao, Yu Cai, Yujia Hou, Yanjin Wu, Tingting Wei, Lili Li, Zhaojun Duan, Xinran Lu, Jiahui Meng, Haitao Zhou, et al.(Abcam, ab15580), Lysozyme (Abcam, ab108508), GFP (Abcam, ab6556), Isg15 (F‐9) (Santa Cruz Biotechnology, sc‐166755), and PCNA (Proteintech, 60097‐1‐Ig). After washing off the primary antibodies with PBS, the slides

(19) Pseudorabies Virus IE180 Inhibits Virus Replication by Activating the Type I Interferon PathwayMicroorganismsJune 16, 2025Feiyang Zheng, Jingjing Song, Xuan Chen, Dongyue Xing, Rulan Bai, Changyong Cheng, Jin Yuan, Rui ZhangCell Signaling Technology (Danvers, MA, USA); Flag (F1804, Sigma-Aldrich, St. Louis, MO, USA), ISG15 (sc-166755, Santa Cruz Biotechnology, Dallas, TX, USA), tubulin (PM054, MBL, Woburn, MA, USA), GAPDH (ab8245, Abcam,

(20) Kaposi''s sarcoma-associated herpesvirus induces mitochondrial fission to evade host immune responses and promote viral productionNature microbiologyJune 1, 2025Zhu Q, McElroy R, Machhar JS, Cassel J, Zheng Z, Mansoori B, Guo H, Guo S, Pangilinan C, Liang J, et al.include: mouse anti-TOM20 (F-10) (sc-17764; 1:50), mouse anti-V5 (sc-271944; 1:100), mouse anti-ISG15 (sc 166755; 1:50), mouse monoclonal anti-MxB (H-7) (sc-271527; 1:50), mouse anti-ISG15(F-9) (sc-66755; 1:50) from

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ISG15 (F-9) Antibody

ISG15 (F-9) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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ISG15 (F-9) Antibody from Santa Cruz Biotechnology, Inc.

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