The Rabbit Anti-HTR1B / 5-HT2B Receptor Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to HTR2B. This antibody recognizes Human, Horse, Non-Human Primate, and Other Mammalian antigen. The Rabbit Anti-HTR1B / 5-HT2B Receptor Antibody has been shown to work in the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
5-HT2B, a Serotonin Receptor, activates phospholipase C upon binding serotonin, which results in a rise in intracellular calcium. It is known that 5-HT2B regulates cardiovascular function during development and in adulthood; mice lacking functional 5-HT2B receptors died of heart defects during gestation or neonatally, and adult mutant mice displayed cardiopathy, including myocyte disarray and ventricular dilation