MyBioSource.com's Rabbit Anti-Stromal Cell Derived Factor 1alpha Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot. The Rabbit Anti-Stromal Cell Derived Factor 1alpha Antibody was generated using CXCL12 as the antigen and it reacts with Mouse, and Rat.
Description
SDF-1a (stromal cell-derived factor-a), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry